Evidence map›Paper›PMID 33350904›Full record

ArticleEmerging infectious diseases2021

Susceptibility of Domestic Swine to Experimental Infection with Severe Acute Respiratory Syndrome Coronavirus 2.

Brad S Pickering, Greg Smith, Mathieu M Pinette, Carissa Embury-Hyatt, Estella Moffat, Peter Marszal, Charles E Lewis

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
2.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 99 citations in OpenAlex.

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  5. Improving the ONE HEALTH approach: a lesson from SARS-CoV-2 pandemic.Journal of preventive medicine and hygiene · 2024
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Brad S Pickering
Greg Smith
Mathieu M Pinette
Carissa Embury-Hyatt
Estella Moffat
Peter Marszal
Charles E Lewis
Iowa State University · USCanadian Food Inspection Agency · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease, has been shown to infect several species. The role of domestic livestock and associated risks for humans in close contact with food production animals remains unknown for many species. Determining the susceptibility of pigs to SARS-CoV-2 is critical to a One Health approach to manage potential risk for zoonotic transmission. We found that pigs are susceptible to SARS-CoV-2 after oronasal inoculation. Among 16 animals, we detected viral RNA in group oral fluids and in nasal wash from 2 pigs, but live virus was isolated from only 1 pig. Antibodies also were detected in only 2 animals at 11 and 13 days postinoculation but were detected in oral fluid samples at 6 days postinoculation, indicating antibody secretion. These data highlight the need for additional livestock assessment to determine the potential role of domestic animals in the SARS-CoV-2 pandemic.

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralCoronavirus InfectionsDisease SusceptibilityFemaleLymph NodesMaleMouthNasal CavityRectumRNA, ViralSARS-CoV-2SwineVirus SheddingAntibodies, NeutralizingAntibodies, ViralRNA, Viralantibodiescoronaviruscoronavirus diseaseCOVID-19livestockOne Healthpandemicspublic healthrespiratory infectionsSARSSARS-CoV-2severe acute respiratory syndrome coronavirus 2swineviruseszoonoses

Identifiers

PMID33350904
PMCPMC7774549
OpenAlexW3116634221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.