Evidence map›Paper›PMID 33350853›Full record

ArticleEpigenomics2020

Novel methylated DNA markers accurately discriminate Lynch syndrome associated colorectal neoplasia.

Veroushka Ballester, William R Taylor, Seth W Slettedahl, Douglas W Mahoney, Tracy C Yab, Frank A Sinicrope, Clement R Boland, Graham P Lidgard, Marcia R Cruz-Correa, Thomas C Smyrk and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Epigenomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Veroushka BallesterDivision of Digestive & Liver Diseases, Columbia University, New York, NY 10032, USA.ORCID 0000-0003-3093-0658
William R TaylorDivision of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA.
Seth W SlettedahlBiostatistics & Informatics, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-3398-3608
Douglas W MahoneyBiostatistics & Informatics, Mayo Clinic, Rochester, MN 55905, USA.
Tracy C YabDivision of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-9116-8428
Frank A SinicropeDivision of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-2907-1000
Clement R BolandDivision of Gastroenterology, UCSD, San Diego, CA 92093, USA.ORCID 0000
Graham P LidgardExact Sciences, Madison, WI 53719, USA.
Marcia R Cruz-CorreaComprehensive Cancer Center, University of Puerto Rico Medical Sciences Campus, San Juan, PR 00936, USA.
Thomas C SmyrkDepartment of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-6194-7853
Lisa A BoardmanDivision of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-1330-2054
David A AhlquistDivision of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA.
John B KisielDivision of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-3840-5324
Mayo Clinic in Arizona · USMayo Clinic · USColumbia University · USExact Sciences (United States) · USUniversity of California San Diego · USUniversity of Puerto Rico, Medical Sciences Campus · PR

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI GREGORY J. GORES · 2009 to 2026
$22.2M
Hispanic Clinical and Translational Research Education and Career Development ProgramR25MD007607 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Karen G. Martinez Gonzalez, Barbara Segarra-Vazquez · 2012 to 2026
$7.4M
Multi-site Gastrointestinal Cancer Detection by Stool DNA MethylationR37CA214679 · NCI · MAYO CLINIC ROCHESTER · PI KISIEL, JOHN · 2018 to 2024
$2.8M
Eugene and Eva LaneExact SciencesMayo Foundation for Medical Education and ResearchNCI NIH HHS R37 CA214679NIDDK NIH HHS P30 DK084567NIMHD NIH HHS R25 MD007607
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA MethylationAdenomaAgedBiomarkersCase-Control StudiesColorectal Neoplasms, Hereditary NonpolyposisFemaleHumansMaleMiddle AgedBiomarkersbiomarkerscolorectal neoplasmscolorectal physiologycolorectal prevention and controlDNA methylationhereditary nonpolyposis

Identifiers

PMID33350853
PMCPMC7923255
OpenAlexW3116392909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.