Evidence map›Paper›PMID 33350830›Full record

ArticleJournal of the American Chemical Society2021

En Route to the Transformation of Glycoscience: A Chemist's Perspective on Internal and External Crossroads in Glycochemistry.

David Crich

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Stereoselectivity of Galactosylation Reactions In Vacuo.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Elucidating the Stereodirecting Effect of C-4 Acyl Groups on Galactosyl Donors.Angewandte Chemie (International ed. in English) · 2026
    Article
  4. The Formation of Covalent Linkages in Lignocellulosic Biomass via the Oxocarbenium Intermediate.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Article
  5. Article
  6. Iron-Catalyzed Highly Stereospecific Glycosylation with Glycal Epoxides.Angewandte Chemie (International ed. in English) · 2025
    Article
  7. Review
  8. Article
  9. Carbohydrate Synthesis is Entering the Data-Driven Digital Era.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  10. Stereoselective Approaches to β-Linked 2-Deoxy Sugars.Molecules (Basel, Switzerland) · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Regenerative Glycopeptide Scaffolds Enhance BMP-4 Activity To Treat Pediatric Glioma.Regenerative engineering and translational medicine · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David CrichDepartment of Pharmaceutical and Biomedical Sciences, University of Georgia, 250 West Green Street, Athens, Georgia 30602, United States.ORCID 0000-0003-2400-0083

Funding

Methods and Mechanisms in Carbohydrate ChemistryR01GM062160 · NIGMS · WAYNE STATE UNIVERSITY · PI CRICH, DAVID · 2001 to 2024
$7.1M
Shaping Next Generation Aminoglycoside Antibiotics for Treatment of Multidrug-Resistant DiseasesR01AI123352 · NIAID · WAYNE STATE UNIVERSITY · PI CRICH, DAVID · 2016 to 2019
$2.7M
Novel Methods and Technologies for Synthesis of Biomedically Relevant CarbohydratesU01GM125271 · NIGMS · WAYNE STATE UNIVERSITY · PI ANDREANA, PETER R, CRICH, DAVID · 2017 to 2020
$2.4M
NIAID NIH HHS R01 AI123352NIGMS NIH HHS R01 GM062160NIGMS NIH HHS U01 GM125271
6 · The paper itself

Abstract

Carbohydrate chemistry is an essential component of the glycosciences and is fundamental to their progress. This Perspective takes the position that carbohydrate chemistry, or glycochemistry, has reached three crossroads on the path to the transformation of the glycosciences, and illustrates them with examples from the author's and other laboratories. The first of these potential inflexion points concerns the mechanism of the glycosylation reaction and the role of protecting groups. It is argued that the experimental evidence supports bimolecular S

Indexed as

CarbohydratesChemistry, OrganicChemistry, PharmaceuticalGlycosylationStereoisomerismCarbohydrates

Identifiers

PMID33350830
PMCPMC7856254

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.