Evidence map›Paper›PMID 33350779›Full record

Observational studyMedicine2020

Association of malnutrition with postoperative complication risk after curative surgery for oral cancer: Observational study.

Yao-Te Tsai, Chia-Hsuan Lai, Tzu-Hao Huang, Ching-Chuan Hsieh, Ethan I Huang, Yi-Chan Lee, Hsuan-Keng Yeh, Ming-Shao Tsai, Geng-He Chang, Cheng-Ming Hsu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yao-Te TsaiDepartment of Otorhinolaryngology-Head and Neck Surgery.
Chia-Hsuan LaiDepartment of Radiation Oncology.
Tzu-Hao HuangDepartment of Surgery, Chang Gung Memorial Hospital, Chiayi.
Ching-Chuan HsiehDepartment of Surgery, Chang Gung Memorial Hospital, Chiayi.
Ethan I HuangDepartment of Otorhinolaryngology-Head and Neck Surgery.
Yi-Chan LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung.
Hsuan-Keng YehDepartment of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Ming-Shao TsaiDepartment of Otorhinolaryngology-Head and Neck Surgery.
Geng-He ChangDepartment of Otorhinolaryngology-Head and Neck Surgery.
Cheng-Ming HsuDepartment of Otorhinolaryngology-Head and Neck Surgery.
Chiayi Chang Gung Memorial Hospital · TWKeelung Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractMalnutrition is common among patients who have oral cavity squamous cell carcinoma (OSCC), but its effect on the incidence of postoperative complications remains uncertain. Validated nutrition and complication assessment tools were used to evaluate the effects of nutrition on the likelihood of postoperative complications after curative surgery for OSCC.A retrospective study that spanned January 2014 to December 2018 enrolled 70 patients who received curative surgery for OSCC. Nutritional status before surgery was evaluated with the scored Patient-Generated Subjective Global Assessment (PG-SGA), and patients were classified as either well-nourished (rating A) or malnourished (ratings B and C). Complications 30 days after the operation were graded using Clavien-Dindo classification. The perioperative clinicopathological characteristics of the groups were compared, and risk factors for postoperative complications were identified through logistic regression.A total of 44 (62.8%) patients formed the malnourished group, and they tended to be older (P = .03), weigh less (P = .001), have lower Body Mass Index (P = .003), higher PG-SGA scores (P < .001), higher neutrophil-to-lymphocyte ratio (P = .034), more postoperative complications (P < .001), and longer hospital stays (P = .021). Major complications (Clavien-Dindo classification ≥ IIIa) were experienced by 18.5% (n = 13) of patients and were more common in the malnourished group (P = .007). Multivariate logistic regression demonstrated that PG-SGA score ≥4 was an independent risk factor for postoperative complications (hazard ratio = 4.929, P = .008).Malnutrition defined using the PG-SGA is an independent risk factor for postoperative complications of curative surgery in patients with OSCC. More prospective studies are warranted to confirm our findings.

Indexed as

MalnutritionNutritional StatusPostoperative ComplicationsCarcinoma, Squamous CellFemaleHumansMaleMiddle AgedMouth NeoplasmsNutrition AssessmentOral Surgical ProceduresRisk AssessmentRisk Factors

Identifiers

PMID33350779
PMCPMC7769301
OpenAlexW3116319240

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.