ReviewJournal of veterinary pharmacology and therapeutics2021
Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part III: Sheep and goat.
Review in Journal of veterinary pharmacology and therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review and Meta-Analysis of Physiologic Variables in Sheep Fetuses.Comparative medicine · 2024Pooled it
- Spatiotemporal screening and functional analysis of gut microbiota associated with abdominal fat deposition in breeder broiler hens.Poultry science · 2026Article
- Towards clinical translation of nanomedicines: Formulation scale-up and model systems.Advanced drug delivery reviews · 2026Review
- Large Animal Models for Preclinical Evaluation of Heart Valve Prostheses, Left Ventricular Assist Devices and Total Artificial Hearts: A Narrative Review.Biomimetics (Basel, Switzerland) · 2026Review
- Biochar Supplementation Effects on Fresh Goat Meat and Carcass Characteristics.Animals : an open access journal from MDPI · 2026Article
- Effect of sorghum-based diets on the abundance and diversity of ruminal methanogenic archaea in Mashona goats.Frontiers in microbiology · 2026Article
- Pharmacokinetics and Bioavailability of Single-Dose Intramuscular and Intravenous Administration of Thiafentanil in Goats (Capra hircus).Journal of veterinary pharmacology and therapeutics · 2025Article
- A soft robotic total artificial hybrid heart.Nature communications · 2025Article
- miR-379-5p retards the proliferation and differentiation of goat skeletal muscle satellite cells by targetingFrontiers in veterinary science · 2025Article
- Experimental animal models of acute respiratory distress syndrome: one-hit and two-hit establishment application.Frontiers in immunology · 2025Review
- Expansion of platform physiologically-based pharmacokinetic model for monoclonal antibodies towards different preclinical species: cats, sheep, and dogs.Journal of pharmacokinetics and pharmacodynamics · 2024Article
- Development and application of a physiologically-based pharmacokinetic model for ractopamine in goats.Frontiers in veterinary science · 2024Article
- A physiologically based pharmacokinetic model to optimize the dosage regimen and withdrawal time of cefquinome in pigs.PLoS computational biology · 2023Article
- Calcification in Pulmonary Heart Valve Tissue Engineering: A Systematic Review and Meta-Analysis of Large-Animal Studies.JACC. Basic to translational science · 2023Review
- Review
- Toward assessing the role of dietary fatty acids in lamb's neurological and cognitive development.Frontiers in veterinary science · 2023Article
- An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol, and Penicillin G.Toxicological sciences : an official journal of the Society of Toxicology · 2022Article
- Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part III: Sheep and goat.Journal of veterinary pharmacology and therapeutics · 2021Review
- Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part II: Chicken and turkey.Journal of veterinary pharmacology and therapeutics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
This report is the third in a series of studies that aimed to compile physiological parameters related to develop physiologically based pharmacokinetic (PBPK) models for drugs and environmental chemicals in food-producing animals including swine and cattle (Part I), chickens and turkeys (Part II), and finally sheep and goats (the focus of this manuscript). Literature searches were conducted in multiple databases (PubMed, Google Scholar, ScienceDirect, and ProQuest), with data on relevant parameters including body weight, relative organ weight (% of body weight), cardiac output, relative organ blood flow (% of cardiac output), residual blood volume (% of organ weight), and hematocrit reviewed and statistically summarized. The mean and standard deviation of each parameter are presented in tables. Equations describing the growth curves of sheep and goats are presented in figures. When data are sufficient, parameter values are reported for different ages or production classes of sheep, including fetal sheep, lambs, and market-age sheep (mature sheep). These data provide a reference database for developing standardized PBPK models to predict drug withdrawal intervals in sheep and goats, and also provide a basis for extrapolating PBPK models from major species such as cattle to minor species such as sheep and goats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.