ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021
Need for improvements in simultaneous heart-kidney allocation: The limitation of pretransplant glomerular filtration rate.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 28 citations in OpenAlex.
- Survival Benefit of Heart-Kidney Versus Heart Transplant With or Without Delayed Kidney Transplant.Journal of the American Heart Association · 2026Article
- Simultaneous heart-kidney transplantation outcomes in Asian populations in the United States: A united network for organ sharing database study.JHLT open · 2025Article
- Bridge to simultaneous heart-kidney transplantation via extracorporeal life support: National outcomes in the new heart allocation policy era.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025Article
- Deceased Donor Renal Allograft Utility in Adult Single and Multi-organ Transplantation in the United States.Transplantation direct · 2025Article
- Subsequent kidney transplant after pediatric heart transplant: Prevalence and risk factors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024Article
- Evolutions in Combined Heart-Kidney Transplant.Current heart failure reports · 2024Review
- Center variations in patient selection for simultaneous heart-kidney transplantation.Clinical transplantation · 2022Article
- Optimal patient selection for simultaneous heart-kidney transplant: A modified cost-effectiveness analysis.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Article
- Current considerations for heart-kidney transplantation.Frontiers in transplantation · 2022Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The incidence of simultaneous heart-kidney transplant (SHK) has increased markedly in the last 15 years. There are no universally agreed upon indications for SHK vs. heart alone (HA) transplant, and center evaluation processes vary widely. We utilized Scientific Registry of Transplant Recipients data from 2003 to 2017 to quantify changes in the practice of SHK, examine the survival of SHK vs. HA, and identify patients with marginal benefit from SHK. We used Kaplan-Meier curves and Cox proportional hazards to assess differences in survival. The incidence of SHK increased more than fourfold between 2003 and 2017 from 1.6% to 6.6% of total hearts transplanted, while the proportion of dialysis-dependent patients undergoing SHK has remained constant. SHK was associated with increased survival in dialysis-dependent patients (Median Survival SHK: 12.6 vs. HA: 7.1 years p < .0001) but not with nondialysis-dependent patients (Median Survival SHK: 12.5 vs. HA 12.3, p = .24). The marginal effect of SHK in decreasing the hazard of death diminished with increasing eGFR. Delayed graft function occurred in 26% of SHK recipients. Posttransplant chronic dialysis was similar for both operations (6.4% of HA and 6.0% of SHK). Further study is needed to define patients who benefit from SHK.
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