Evidence map›Paper›PMID 33350048›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Single center results of simultaneous pancreas-kidney transplantation in patients with type 2 diabetes.

Phuoc H Pham, Lily N Stalter, Eric J Martinez, Jesse F Wang, Bridget M Welch, Glen Leverson, Nicholas Marka, Talal Al-Qaoud, Didier Mandelbrot, Sandesh Parajuli and 4 more

Open access · greenAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Continuous Glucose Monitoring Before and After Simultaneous Pancreas-Kidney Transplantation: Insights from a Real-World Clinical Setting.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Simultaneous Pancreas and Kidney Transplantation in Patients With Type 2 Diabetes Mellitus.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  8. Article
  9. Article
  10. Generating strategies for a national comeback in pancreas transplantation: A Delphi survey and US conference report.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  11. Article
  12. Analysis of Rejection, Infection and Surgical Outcomes in Type I Versus Type II Diabetic Recipients After Simultaneous Pancreas-Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  13. Article
  14. Multi-Centre UK Analysis of Simultaneous Pancreas and Kidney (SPK) Transplant in Recipients With Type 2 Diabetes Mellitus.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  15. Article
  16. Diabetes in Kidney Transplantation.Advances in chronic kidney disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Phuoc H PhamDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Lily N StalterDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Eric J MartinezDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Jesse F WangDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Bridget M WelchDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Glen LeversonDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Nicholas MarkaDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Talal Al-QaoudDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0002-5215-6408
Didier MandelbrotDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Sandesh ParajuliDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0003-1667-7465
Hans W SollingerDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Dixon KaufmanDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Robert R RedfieldDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Jon S OdoricoDivision of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0003-1096-464X
University of Wisconsin–Madison · US

Funding

Surgery Summer Research Experience for Medical StudentsT35DK062709 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI MEZRICH, JOSHUA D · 2006 to 2023
$870k
NIDDK NIH HHS T35 DK062709
6 · The paper itself

Abstract

Studies have found similar outcomes of Simultaneous Pancreas-Kidney transplantation (SPKT) in patients with Type 2 (T2D) and Type 1 diabetes (T1D). However, there are scarce data evaluating the association of recipient factors such as age, BMI, or pretransplant insulin requirements with outcomes, thus the criteria for the optimal recipient selection remains unclear. In this study, 284 T1D and 39 T2D patients, who underwent SPKT between 2006 and 2017 with 1 year of follow-up at minimum, were assessed for potential relationship of pretransplant BMI and insulin requirements with posttransplant diabetes and pancreatic graft failure. Kaplan-Meier analysis showed similar rates of freedom from posttransplant diabetes (94.7% T2D vs. 92.3% T1D at 1 yr, and 88.1% T2D vs. 81.1% T1D at 5 yrs) and graft survival (89.7% T2D vs. 90.4% T1D at 1 yr, and 89.7% T2D vs. 81.2% T1D at 5 yrs). There was no significant association between BMI or pretransplant insulin requirements with posttransplant diabetes occurrence in either T1D (p = .10, .43, respectively) or T2D (p = .12, .63) patients in the cohort; or with graft failure (T1D: p = .40, .09; T2D: p = .71, .28). These observations suggest a less restricted approach to selective use of SPKT in patients with T2D.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Kidney TransplantationPancreas TransplantationHumansInsulinPancreasInsulinclinical decision-makingclinical research/practicediabetes: new onset/posttransplantdiabetes: type 2endocrinology/diabetologyhealth services and outcomes researchimmunosuppression/immune modulationobesitypancreas/simultaneous pancreas-kidney transplantationrecipient selection

Identifiers

PMID33350048
PMCPMC8217396
OpenAlexW3114904905

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.