Evidence map›Paper›PMID 33349792›Full record

ReviewMeta gene2021

Essential interpretations of bioinformatics in COVID-19 pandemic.

Manisha Ray, Mukund Namdev Sable, Saurav Sarkar, Vinaykumar Hallur

Abstract readReview
In one paragraph

Review in Meta gene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. GenoDense-Net: unraveling the genomic puzzle of the global pathogen.Tropical diseases, travel medicine and vaccines · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Johann Gregor Mendel: the victory of statistics over human imagination.European journal of human genetics : EJHG · 2023
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manisha RayDepartment of Pathology & Lab Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.
Mukund Namdev SableDepartment of ENT, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.
Saurav SarkarDepartment of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.
Vinaykumar HallurDepartment of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The currently emerging pathogen SARS-CoV-2 has produced the global pandemic crisis by causing COVID-19. The unique and novel genetic makeup of SARS-CoV-2 has created hurdles in biological research, due to which the potential drug/vaccine candidates have not yet been discovered by the scientific community. Meanwhile, the advantages of bioinformatics in viral research had created a milestone since last few decades. The exploitation of bioinformatics tools and techniques has successfully interpreted this viral genomics architecture. Some major in silico studies involving next-generation sequencing, genome-wide association studies, computer-aided drug design etc. have been effectively applied in COVID-19 research methodologies and discovered novel information on SARS-CoV-2 in several ways. Nowadays the implementation of in silico studies in COVID-19 research has not only sequenced the SARS-CoV-2 genome but also properly analyzed the sequencing errors, evolutionary relationship, genetic variations, putative drug candidates against SARS-CoV-2 viral genes etc. within a very short time period. These would be very needful towards further research on COVID-19 pandemic and essential for vaccine development against SARS-CoV-2 which will save public health.

Indexed as

BioinformaticsCOVID-19Drug designGenome wide association studyNext generation sequencingSARS-CoV-2

Identifiers

PMID33349792
PMCPMC7744275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.