Evidence map›Paper›PMID 33349502›Full record

ArticleJournal of cardiothoracic and vascular anesthesia2021

MAGGIC, STS, and EuroSCORE II Risk Score Comparison After Aortic and Mitral Valve Surgery.

David X Zhuo, Kenneth C Bilchick, Kajal P Shah, Nishaki K Mehta, Hunter Mwansa, Kanasa Nkanza-Kabaso, Younghoon Kwon, Khadijah K Breathett, Ebony J Hilton-Buchholz, Sula Mazimba

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In one paragraph

Article in Journal of cardiothoracic and vascular anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  4. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

David X ZhuoUniversity of Virginia Health System, Department of Medicine, Division of Cardiovascular Medicine, Charlottesville, VA. Electronic address: david.x.zhuo@gmail.com.
Kenneth C BilchickUniversity of Virginia Health System, Department of Medicine, Division of Cardiovascular Medicine, Charlottesville, VA.
Kajal P ShahUniversity of Virginia Health System, Department of Medicine, Division of Cardiovascular Medicine, Charlottesville, VA.
Nishaki K MehtaUniversity of Virginia Health System, Department of Medicine, Division of Cardiovascular Medicine, Charlottesville, VA.
Hunter MwansaOSF Saint Francis Medical Center, Peoria, IL.
Kanasa Nkanza-KabasoUniversity of Cape Town, Groote Schuur Hospital, Cape Town, South Africa.
Younghoon KwonUniversity of Washington Medical Center, University of Washington Division of Cardiology, Harborview Medical Center, Seattle, WA.
Khadijah K BreathettUniversity of Arizona College of Medicine, Division of Cardiology/Sarver Heart Center, Tucson, AZ.
Ebony J Hilton-BuchholzUniversity of Virginia Health System, Department of Anesthesiology, Charlottesville, VA.
Sula MazimbaUniversity of Virginia Health System, Department of Medicine, Division of Cardiovascular Medicine, Charlottesville, VA.
University of Virginia Health System · USOSF Saint Francis Medical Center · USUniversity of Arizona · USUniversity of Cape Town · ZAUniversity of Washington Medical Center · US

Funding

Addressing Individual Provider Bias and Group Decision-Making in Selection of Advanced Heart Failure Therapies in Racial/Ethnic MinoritiesK01HL142848 · NHLBI · UNIVERSITY OF ARIZONA · PI BREATHETT, KHADIJAH · 2018 to 2021
$858k
NHLBI NIH HHS K01 HL142848NHLBI NIH HHS L30 HL148881
6 · The paper itself

Abstract

objectivesTo compare the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) risk score with the established Society of Thoracic Surgeons (STS) and EuroSCORE II risk prediction models regarding mortality discrimination after aortic and mitral valve surgery.

designRetrospective cohort study.

settingSingle tertiary academic medical center.

participantsA total of 259 patients who underwent open aortic valve replacement or open mitral valve repair/replacement from 2009-2014.

interventionsRetrospective chart review. MEASUREMENTS AND MAIN

resultsMAGGIC, STS, and EuroSCORE II risk scores for each patient were studied using binary logistic regression and receiver operating characteristic analysis for the primary endpoint of one-year mortality and secondary endpoint of 30-day mortality. One-year mortality C-statistics were similar across risk scores (STS 0.709, 95% confidence interval [CI] 0.578-0.841; MAGGIC 0.673, 95% CI 0.547-0.799; EuroSCORE II 0.642, 95% CI 0.521-0.762; p = 0.56 between STS and MAGGIC; p = 0.20 between STS and EuroSCORE II; and p = 0.69 between MAGGIC and EuroSCORE II). Thirty-day mortality C-statistics also were similar between STS (0.797, 95% CI 0.655-0.939; p < 0.0001 v null hypothesis), MAGGIC (0.721, 95% CI 0.581-0.860; p = 0.33 v STS), and EuroSCORE II (0.688, 95% CI 0.557-0.818; p = 0.06 v STS; p = 0.68 v MAGGIC).

conclusionsThe MAGGIC risk score performs similarly to STS and EuroSCORE II risk models in mortality discrimination after aortic and mitral valve surgery, albeit in a small sample size. This finding has important implications in establishing MAGGIC as a viable prognostic model in this population subset, with fewer variables and ease of use representing key advantages over STS and EuroSCORE II.

Indexed as

Aortic Valve StenosisHeart FailureHeart Valve Prosthesis ImplantationAortic ValveHumansMitral ValveRetrospective StudiesRisk AssessmentRisk Factorsaortic valve replacementEuroSCORE IIMAGGICMeta-Analysis Global Group in Chronic Heart Failuremitral valve repair/replacementmortalityperioperative risk assessmentSociety of Thoracic SurgeonsSTSvalvular heart surgery

Identifiers

PMID33349502
PMCPMC8076089
OpenAlexW3107615490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.