Evidence map›Paper›PMID 33349133›Full record

ReviewTissue engineering. Part C, Methods2021

Skin-Nerve Co-Culture Systems for Disease Modeling and Drug Discovery.

Stacey C Schutte, Feni Kadakia, Steve Davidson

Open access · greenAbstract readReview
In one paragraph

Review in Tissue engineering. Part C, Methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Skin innervation and itsFrontiers in cellular neuroscience · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Cellular Pathogenesis of Chemotherapy-Induced Peripheral Neuropathy: Insights FromFrontiers in pain research (Lausanne, Switzerland) · 2022
    Review
  8. Fibroblasts as an experimental model system for the study of comparative physiology.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stacey C SchutteDepartment of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA.
Feni KadakiaDepartment of Anesthesiology, Pain Research Center, and Neuroscience Graduate Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Steve DavidsonDepartment of Anesthesiology, Pain Research Center, and Neuroscience Graduate Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
University of Cincinnati Medical Center · USUniversity of Cincinnati · US

Funding

Thalamo-Limbic Circuits in PainR01NS107356 · NINDS · UNIVERSITY OF CINCINNATI · PI DAVIDSON, STEVE · 2018 to 2022
$1.8M
NINDS NIH HHS R01 NS107356
6 · The paper itself

Abstract

Prominent clinical problems related to the skin-nerve interface include barrier dysfunction and erythema, but it is the symptoms of pain and itch that most often lead patients to seek medical treatment. Tissue-engineered innervated skin models provide an excellent solution for studying the mechanisms underlying neurocutaneous disorders for drug screening, and cutaneous device development. Innervated skin substitutes provide solutions beyond traditional monolayer cultures and have advantages that make them preferable to

Indexed as

Drug DiscoverySkin, ArtificialAnimalsCoculture TechniquesEpidermisHumansSkinco-culturenerveskin

Identifiers

PMID33349133
PMCPMC8020509
OpenAlexW3117269578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.