Evidence map›Paper›PMID 33348867›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Efficiency of a Tetracycline-Adjuvant Combination Against Multidrug Resistant

Azza Troudi, Meha Fethi, Mohamed Selim El Asli, Jean Michel Bolla, Naouel Klibi, Jean Michel Brunel

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Azza TroudiFaculté de Pharmacie, Aix Marseille Universite, INSERM, SSA, MCT, 13385 Marseille, France.
Meha FethiLaboratory of Microorganisms and Active Biomolecules, Department of Biology, Faculty of Sciences of Tunis, University of Tunis, Tunis 1008, Tunisia.
Mohamed Selim El AsliService of Microbiology, Military Hospital of Tunis HMPIT, Tunis 1008, Tunisia.
Jean Michel BollaFaculté de Pharmacie, Aix Marseille Universite, INSERM, SSA, MCT, 13385 Marseille, France.ORCID 0000-0003-3892-4340
Naouel KlibiLaboratory of Microorganisms and Active Biomolecules, Department of Biology, Faculty of Sciences of Tunis, University of Tunis, Tunis 1008, Tunisia.
Jean Michel BrunelFaculté de Pharmacie, Aix Marseille Universite, INSERM, SSA, MCT, 13385 Marseille, France.ORCID 0000-0002-9355-8980
Tunis University · TNInserm · FRMilitary Hospital of Tunis · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing number of multidrug resistant strains in Tunisia has become a serious health concern contributing to high rate of mortality and morbidity. Since current antibiotics are rapidly becoming ineffective, novel strategies to combat resistance are needed. Recently, we demonstrated that combination of a tetracycline antibiotic with various polyaminoisoprenyl adjuvants can sustain the life span and enhance the activity of these drugs against

Indexed as

antibiotic adjuvantsdoxycyclineminocyclinepolyaminespolyaminoisoprenyl derivativesPseudomonas aeruginosa clinical strains

Identifiers

PMID33348867
PMCPMC7766271
OpenAlexW3112031933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.