Evidence map›Paper›PMID 33348802›Full record

ArticleNutrients2020

An Integrated Analysis of miRNA and Gene Expression Changes in Response to an Obesogenic Diet to Explore the Impact of Transgenerational Supplementation with Omega 3 Fatty Acids.

Karla Fabiola Corral-Jara, Laura Cantini, Nathalie Poupin, Tao Ye, Jean Paul Rigaudière, Sarah De Saint Vincent, Alexandre Pinel, Béatrice Morio, Frédéric Capel

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Karla Fabiola Corral-JaraUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, Institut National de Recherche pour L'agriculture, L'alimentation et L'environnement (INRAE), Faculté de Médecine, F-63000 Clermont-Ferrand, France.
Laura CantiniComputational Systems Biology Team, Institut de Biologie de l'Ecole Normale Supérieure, CNRS, INSERM, Ecole Normale Supérieure, Université PSL, 75005 Paris, France.
Nathalie PoupinToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31027 Toulouse, France.ORCID 0000-0002-3393-1405
Tao YeGenomEast Platform, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 1 rue Laurent Fries/BP 10142/, 67404 Illkirch, France.
Jean Paul RigaudièreUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, Institut National de Recherche pour L'agriculture, L'alimentation et L'environnement (INRAE), Faculté de Médecine, F-63000 Clermont-Ferrand, France.
Sarah De Saint VincentUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, Institut National de Recherche pour L'agriculture, L'alimentation et L'environnement (INRAE), Faculté de Médecine, F-63000 Clermont-Ferrand, France.
Alexandre PinelUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, Institut National de Recherche pour L'agriculture, L'alimentation et L'environnement (INRAE), Faculté de Médecine, F-63000 Clermont-Ferrand, France.
Béatrice MorioCarMeN Laboratory, INSERM U1060, INRAE U1397, Université Lyon 1, 69310 Pierre Bénite, France.
Frédéric CapelUnité de Nutrition Humaine (UNH), Université Clermont Auvergne, Institut National de Recherche pour L'agriculture, L'alimentation et L'environnement (INRAE), Faculté de Médecine, F-63000 Clermont-Ferrand, France.ORCID 0000-0002-0133-0277
Université Clermont Auvergne · FRCentre National de la Recherche Scientifique · FRInstitut de génétique et de biologie moléculaire et cellulaire · FRUniversité Claude Bernard Lyon 1 · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

Sofiproteol N.A.
6 · The paper itself

Abstract

Insulin resistance decreases the ability of insulin to inhibit hepatic gluconeogenesis, a key step in the development of metabolic syndrome. Metabolic alterations, fat accumulation, and fibrosis in the liver are closely related and contribute to the progression of comorbidities, such as hypertension, type 2 diabetes, or cancer. Omega 3 (

Indexed as

AnimalsDietary SupplementsDiet, High-FatDisease Models, AnimalFatty Acids, Omega-3Gene ExpressionLiverMaleMetabolic SyndromeMiceMice, Inbred C57BLMicroRNAsFatty Acids, Omega-3MicroRNAslivermetabolic syndromemicroRNAobesityomega 3 fatty acidstranscriptome

Identifiers

PMID33348802
PMCPMC7765958
OpenAlexW3112259685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.