Evidence map›Paper›PMID 33348734›Full record

ArticleMolecules (Basel, Switzerland)2020

GPCR Activation States Induced by Nanobodies and Mini-G Proteins Compared by NMR Spectroscopy.

Philip Rößler, Daniel Mayer, Ching-Ju Tsai, Dmitry B Veprintsev, Gebhard F X Schertler, Alvar D Gossert

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Arrestin recognizes GPCRs independently of the receptor state.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Philip RößlerInstitute of Molecular Biology and Biophysics, ETH Zürich, 8093 Zürich, Switzerland.ORCID 0000-0003-1378-2817
Daniel MayerPaul Scherrer Institute, Division of Biology and Chemistry (BIO), 5232 Villigen, Switzerland.
Ching-Ju TsaiPaul Scherrer Institute, Division of Biology and Chemistry (BIO), 5232 Villigen, Switzerland.
Dmitry B VeprintsevCentre of Membrane Proteins and Receptors (COMPARE), University of Nottingham, Midlands NG7 2RD, UK.
Gebhard F X SchertlerPaul Scherrer Institute, Division of Biology and Chemistry (BIO), 5232 Villigen, Switzerland.ORCID 0000-0002-5846-6810
Alvar D GossertInstitute of Molecular Biology and Biophysics, ETH Zürich, 8093 Zürich, Switzerland.
Paul Scherrer Institute · CHETH Zurich · CHUniversity of Nottingham · GB

Funding

Novartis Stiftung für Medizinisch-Biologische Forschung #17B113Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_179319
6 · The paper itself

Abstract

In this work, we examine methyl nuclear magnetic resonance (NMR) spectra of the methionine ε-[

Indexed as

Binding SitesCrystallography, X-RayGTP-Binding ProteinsHumansNuclear Magnetic Resonance, BiomolecularPindololProtein ConformationReceptors, Adrenergic, beta-1Receptors, G-Protein-CoupledSignal TransductionSingle-Chain AntibodiesSingle-Domain AntibodiesTurkeyGTP-Binding ProteinsNb80 nanobodyPindololReceptors, Adrenergic, beta-1Receptors, G-Protein-CoupledSingle-Chain AntibodiesSingle-Domain AntibodiesGPCRmini-GnanobodyNMR

Identifiers

PMID33348734
PMCPMC7767065
OpenAlexW3111419794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.