Evidence map›Paper›PMID 33348680›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Seasonality Modulates the Cellular Antioxidant Activity and Antiproliferative Effect of Sonoran Desert Propolis.

Pablo Mendez-Pfeiffer, Efrain Alday, Ana Laura Carreño, Jorge Hernández-Tánori, Beatriz Montaño-Leyva, Jesús Ortega-García, Judith Valdez, Adriana Garibay-Escobar, Javier Hernandez, Dora Valencia and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Pablo Mendez-PfeifferDepartment of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora C.P. 83000, Mexico.ORCID 0000-0002-8627-3565
Efrain AldayDepartment of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora C.P. 83000, Mexico.ORCID 0000-0003-3680-2235
Ana Laura CarreñoDepartment of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora C.P. 83000, Mexico.
Jorge Hernández-TánoriDepartment of Chemical Biological and Agropecuary Sciences, University of Sonora, Av. Universidad and Irigoyen, Caborca, Sonora C.P. 83600, Mexico.
Beatriz Montaño-LeyvaDepartamento de Investigacion y Posgrado en Alimentos, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora C.P. 83000, Mexico.
Jesús Ortega-GarcíaDepartment of Chemical Biological and Agropecuary Sciences, University of Sonora, Av. Universidad and Irigoyen, Caborca, Sonora C.P. 83600, Mexico.
Judith ValdezDepartment of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora C.P. 83000, Mexico.
Adriana Garibay-EscobarDepartment of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora C.P. 83000, Mexico.ORCID 0000-0002-5985-8736
Javier HernandezUnidad de Servicios de Apoyo en Resolución Analítica, Universidad Veracruzana, Xalapa, Veracruz C.P. 91190, Mexico.
Dora ValenciaDepartment of Chemical Biological and Agropecuary Sciences, University of Sonora, Av. Universidad and Irigoyen, Caborca, Sonora C.P. 83600, Mexico.ORCID 0000-0002-3275-5243
Carlos VelazquezDepartment of Chemistry-Biology, University of Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo, Sonora C.P. 83000, Mexico.
Universidad de Sonora · MXUniversidad Veracruzana · MX

Funding

Programa para el Desarrollo Profesional Docente, para el Tipo Superior (PRODEP) UNISON-PTC-207
6 · The paper itself

Abstract

The main chemical composition and pharmacological potential of propolis from arid and semi-arid regions of the Sonoran Desert have been previously reported. Caborca propolis (CP), from an arid zone of the Sonoran Desert, has shown a polyphenolic profile that suggests a mixed plant origin, presenting poplar-type markers, as well as a 6-methoxylated flavonoid, xanthomicrol, characteristic of Asteraceae plants. In addition, CP has shown significant antioxidant properties and antiproliferative activity on cancer cells. In this study, we analyzed the influence of collection time on the chemical constitution, antiproliferative activity and protective capacity of CP against reactive oxygen species (ROS), by using HPLC-UV-diode array detection (DAD) analysis, 3-(4,5-dimethylthiazol-2-yl)-2,5-Dimethyltetrazoliumbromide (MTT) and 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assays, as well as cellular antioxidant activity (CAA) assay on murine B-cell lymphoma M12.C3.F6 cells. HPLC-UV-DAD analyses of seasonally collected CP (one-year period) revealed quantitative differences among the most abundant CP constituents: pinocembrin, galangin, chrysin and pinobanksin-3-

Indexed as

antiproliferative effectcellular antioxidant activitymixed poplar-type propolispolyphenolic compositionseasonal effect

Identifiers

PMID33348680
PMCPMC7765891
OpenAlexW3111831677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.