Evidence map›Paper›PMID 33348659›Full record

ArticleCells2020

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling.

Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W Fluhr, Laurent Misery, Raphaële Le Garrec

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ophélie PierreEA4685 Laboratory of Interactions Neurons-Keratinocytes (LIEN), Faculty of Medicine and Health Sciences, University Brest, F-29200 Brest, France.ORCID 0000-0002-3954-5484
Maxime FouchardEA4685 Laboratory of Interactions Neurons-Keratinocytes (LIEN), Faculty of Medicine and Health Sciences, University Brest, F-29200 Brest, France.
Paul BuscagliaInsermUMR1227, Lymphocytes B et Autoimmunity, University Brest, F-29200 Brest, France.ORCID 0000-0002-6080-2983
Nelig Le GouxInsermUMR1227, Lymphocytes B et Autoimmunity, University Brest, F-29200 Brest, France.
Raphaël LeschieraEA4685 Laboratory of Interactions Neurons-Keratinocytes (LIEN), Faculty of Medicine and Health Sciences, University Brest, F-29200 Brest, France.
Olivier MignenInsermUMR1227, Lymphocytes B et Autoimmunity, University Brest, F-29200 Brest, France.ORCID 0000-0001-7913-6119
Joachim W FluhrEA4685 Laboratory of Interactions Neurons-Keratinocytes (LIEN), Faculty of Medicine and Health Sciences, University Brest, F-29200 Brest, France.
Laurent MiseryEA4685 Laboratory of Interactions Neurons-Keratinocytes (LIEN), Faculty of Medicine and Health Sciences, University Brest, F-29200 Brest, France.ORCID 0000-0001-8088-7059
Raphaële Le GarrecEA4685 Laboratory of Interactions Neurons-Keratinocytes (LIEN), Faculty of Medicine and Health Sciences, University Brest, F-29200 Brest, France.ORCID 0000-0002-0269-9076
Centre Hospitalier Régional Universitaire de Brest · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Red tides involving

Indexed as

AnimalsCalciumCathepsinsCells, CulturedDipeptidesEvoked PotentialsHumansIsoxazolesKeratinocytesMarine ToxinsOxocinsPolyether ToxinsProtein Kinase CRatsRats, WistarReceptor, PAR-25-isoxazoyl-cyclohexylalanyl-isoleucyl-spiroindane-1,4'-piperidinebrevetoxinCalciumcathepsin SCathepsinsDipeptidesIsoxazolesMarine ToxinsOxocinsPolyether ToxinsProtein Kinase CReceptor, PAR-2Recombinant ProteinsSubstance PTRPV Cation Channelsbiased pathwaybrevetoxincanonical pathwaycathepsin SciguatoxinPAR2sensory disorderssubstance P

Identifiers

PMID33348659
PMCPMC7767211
OpenAlexW3112920896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.