Evidence map›Paper›PMID 33348567›Full record

ArticleJournal of clinical medicine2020

Oral Microbiome Signatures in Hematological Cancers Reveal Predominance of

Jean-Luc C Mougeot, Micaela F Beckman, Holden C Langdon, Michael T Brennan, Farah Bahrani Mougeot

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Article
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  7. Article
  8. Saliva assay: a call for methodological standardization.Journal of periodontal & implant science · 2025
    Review
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  10. Article
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  12. Article
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  17. Review
  18. Frontiers in microbiology · 2021
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jean-Luc C MougeotCarolinas Medical Center-Atrium Health, 1000 Blythe Blvd., Charlotte, NC 28203, USA.
Micaela F BeckmanCarolinas Medical Center-Atrium Health, 1000 Blythe Blvd., Charlotte, NC 28203, USA.
Holden C LangdonCarolinas Medical Center-Atrium Health, 1000 Blythe Blvd., Charlotte, NC 28203, USA.
Michael T BrennanCarolinas Medical Center-Atrium Health, 1000 Blythe Blvd., Charlotte, NC 28203, USA.
Farah Bahrani MougeotCarolinas Medical Center-Atrium Health, 1000 Blythe Blvd., Charlotte, NC 28203, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endogenous microbiome of healthy individuals in oral cavities is diverse, representing over 700 bacterial species. Imbalance in oral and gut microbiome composition and associated gene expression has been linked to different forms of hematological (blood) cancers. Our objective is to compare oral microbiome profiles of patients with blood cancers (BC group: N = 39 patients, n = 124 oral samples) to those of healthy control subjects (HC group: N = 27 subjects, n = 100 oral samples). Saliva samples and swabs of buccal mucosa, supragingival plaque, and tongue were collected from blood cancer patients and healthy controls. Next-generation sequencing (16S-rRNA gene V3-V4 region) was used to determine the relative abundance of bacterial taxa present at the genus and species levels. Differences in oral microbiome

Indexed as

Actinomyceshematological or blood cancersLEfSe biomarkersnext-generation 16S sequencingoral microbiome

Identifiers

PMID33348567
PMCPMC7767039

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.