Evidence map›Paper›PMID 33348220›Full record

SynthesisJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2021

Prevalence, clinical characteristics, and outcomes of pediatric COVID-19: A systematic review and meta-analysis.

Sujan Badal, Kalpana Thapa Bajgain, Sujeena Badal, Rama Thapa, Bishnu B Bajgain, Maria Jose Santana

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  11. Clinical Outcomes of Pediatric Cancer Patients with COVID-19: A Cross-Sectional Study.International journal of hematology-oncology and stem cell research · 2024
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sujan BadalSchool of Medicine, University of Minnesota, 420 Delaware St. SE, Minneapolis, MN, 55455, USA. Electronic address: badal014@umn.edu.
Kalpana Thapa BajgainAabKa Research & Consulting, Calgary, Alberta, Canada. Electronic address: k.thapab@aabka.ca.
Sujeena BadalBLH Technologies, INC, Rockville, MD, USA. Electronic address: sbadal@blhtech.com.
Rama ThapaFaculty of Health Sciences, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, T1K 3M4, Canada. Electronic address: rama.thapa@uleth.ca.
Bishnu B BajgainDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada. Electronic address: bishnu.bajgain@ucalgary.ca.
Maria Jose SantanaDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada. Electronic address: mjsantan@ucalgary.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe novel coronavirus pandemic is an ongoing challenge faced by the public and health care systems around the globe. Majority of information and evidence gathered so far regarding COVID-19 has been derived from data and studies in adult populations. Crucial information regarding the characterization, clinical symptomatology, sequelae, and overall outcomes in the pediatric population is lacking. As such, we aimed to conduct a comprehensive meta-analysis and systematic review to collect and analyze current evidence about COVID-19 in the pediatric population.

methodA systematic search and review of scientific literatures was conducted following the PRISMA guidelines using PubMed, Embase, Scopus, Medline, and Google Scholar databases. All relevant studies until June 16, 2020 were included. Studies were reviewed for methodological quality, and random-effects model was used to conduct the primary meta-analysis. I

resultsWe reviewed 20 eligible studies that included 1810 pediatric patient population (<21 yo) with PCR tested COVID-19 positivity. In pooled data, majority (25 % [CI 18-32], I

conclusionCOVID-19 is prevalent across all pediatric age-groups and presents with varying degree of symptomology. However, children have a milder course of the disease with extremely favorable prognosis. Laboratory and radiological features are inconsistent and require further investigations. Additional studies are needed on this topic to corroborate findings and establish evidence-based and consistent characterization of COVID-19 in the pediatric population.

Indexed as

PandemicsChildCOVID-19HumansPrevalenceSARS-CoV-2Clinical characteristicsCOVID-19Meta-analysisOutcomesPediatricSystematic review

Identifiers

PMID33348220
PMCPMC7723460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.