Evidence map›Paper›PMID 33348034›Full record

SynthesisJournal of pain and symptom management2021

The Impact of Specialty Palliative Care in Pediatric Oncology: A Systematic Review.

Erica C Kaye, Meaghann S Weaver, Leila Hamzi DeWitt, Elizabeth Byers, Sarah E Stevens, Joe Lukowski, Brandon Shih, Kristina Zalud, Jacob Applegarth, Hong-Nei Wong and 3 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of pain and symptom management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
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  19. Observational
  20. Paediatric palliative care in cancer.Ecancermedicalscience · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 1 country.

Erica C KayeDivision of Quality of Life and Palliative Care, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. Electronic address: erica.kaye@stjude.org.
Meaghann S WeaverDivision of Pediatric Palliative Care, Children's Hospital and Medical Center, Omaha, Nebraska, USA.
Leila Hamzi DeWittDepartment of Pediatrics, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.
Elizabeth ByersUniversity of Alabama at Birmingham, Birmingham, Alabama, USA.
Sarah E StevensDepartments of Psychosocial Oncology and Palliative Care and Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Joe LukowskiThe University of Nebraska, Omaha, Nebraska, USA.
Brandon ShihRollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Kristina ZaludSt. Louis Children's Hospital, Washington University School of Medicine, St. Louis, Missouri, USA.
Jacob ApplegarthIndiana University School of Medicine, Indianapolis, Indiana, USA.
Hong-Nei WongLane Medical Library & Knowledge Management Center, Stanford University School of Medicine, Stanford, California, USA.
Justin N BakerDivision of Quality of Life and Palliative Care, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Christina K UllrichDepartments of Psychosocial Oncology and Palliative Care and Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts, USA.
AAHPM Research Committee
St. Jude Children's Research Hospital · USBoston Children's Hospital · USChildren's Hospital & Medical Center · USDana-Farber Cancer Institute · USEmory University · USIndiana University School of MedicineStanford University · USSt. Louis Children's Hospital · USUniversity of Alabama at Birmingham · USUniversity of Nebraska at Omaha · USWake Forest University · US

Funding

PROFESSIONAL ONCOLOGY EDUCATION PROGRAMR25CA023944 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI SUZANNE A. GRONEMEYER · 1986 to 2026
$8.3M
NCI NIH HHS R25 CA023944
6 · The paper itself

Abstract

contextChildren with cancer and their families have complex needs related to symptoms, decision-making, care planning, and psychosocial impact extending across the illness trajectory, which for some includes end of life. Whether specialty pediatric palliative care (SPPC) is associated with improved outcomes for children with cancer and their families is unknown.

objectiveWe conducted a systematic review following PRISMA guidelines to investigate outcomes associated with SPPC in pediatric oncology with a focus on intervention delivery, collaboration, and alignment with National Quality Forum domains.

methodsWe searched PubMed, Embase, Scopus, Web of Science, and CINAHL databases from inception until April 2020 and reviewed references manually. Eligible articles were published in English, involved pediatric patients aged 0-18 years with cancer, and contained original data regarding patient and family illness and end-of-life experiences, including symptom management, communication, decision-making, quality of life, satisfaction, and healthcare utilization.

resultsWe screened 6682 article abstracts and 82 full-text articles; 32 studies met inclusion criteria, representing 15,635 unique children with cancer and 342 parents. Generally, children with cancer who received SPPC had improved symptom burden, pain control, and quality of life with decreased intensive procedures, increased completion of advance care planning and resuscitation status documentation, and fewer end-of-life intensive care stays with higher likelihood of dying at home. Family impact included satisfaction with SPPC and perception of improved communication.

conclusionSPPC may improve illness experiences for children with cancer and their families. Multisite studies utilizing comparative effectiveness approaches and validated metrics may support further advancement of the field.

Indexed as

Hospice and Palliative Care NursingNeoplasmsTerminal CareChildHumansPalliative CareQuality of Lifecancerhospiceintegrationpalliative carePediatricreview

Identifiers

PMID33348034
PMCPMC9896574
OpenAlexW3111741921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.