Evidence map›Paper›PMID 33347642›Full record

ArticleMagnetic resonance in medicine2021

Real-time device tracking under MRI using an acousto-optic active marker.

Yusuf S Yaras, Dursun Korel Yildirim, Daniel A Herzka, Toby Rogers, Adrienne E Campbell-Washburn, Robert J Lederman, F Levent Degertekin, Ozgur Kocaturk

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. A Review of Recent Advancements in Sensor-Integrated Medical Tools.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yusuf S YarasGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Micromachined Sensors and Transducers Group, Atlanta, Georgia, USA.ORCID 0000-0002-1117-559X
Dursun Korel YildirimNational Institutes of Health, National Heart Lung and Blood Institute, Bethesda, Maryland, USA.ORCID 0000-0002-1145-939X
Daniel A HerzkaNational Institutes of Health, National Heart Lung and Blood Institute, Bethesda, Maryland, USA.
Toby RogersNational Institutes of Health, National Heart Lung and Blood Institute, Bethesda, Maryland, USA.
Adrienne E Campbell-WashburnNational Institutes of Health, National Heart Lung and Blood Institute, Bethesda, Maryland, USA.ORCID 0000-0002-7169-5693
Robert J LedermanNational Institutes of Health, National Heart Lung and Blood Institute, Bethesda, Maryland, USA.
F Levent DegertekinGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Micromachined Sensors and Transducers Group, Atlanta, Georgia, USA.
Ozgur KocaturkInstitute of Biomedical Engineering, Bogazici University, Kandilli Kampus, Istanbul, Turkey.
National Institutes of Health · USGeorgia Institute of Technology · USKandilli Observatory and Earthquake Research Institute · TR

Funding

Real-time MRI guided cardiovascular interventionZIAHL005062 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2009 to 2025
$21.6M
MRI catheter design and fabricationZIAHL006041 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2014 to 2025
$12.2M
Real-time cardiovascular MRI and co-registration technical developmentZIAHL006039 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2010 to 2024
$10.3M
Innovative Technology for MRI Guided ProceduresZIAHL006213 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CAMPBELL-WASHBURN, ADRIENNE · 2016 to 2025
$5.4M
Acousto-optical RF field sensors for safer diagnostic and interventional MRIR01EB029331 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI DEGERTEKIN, F. LEVENT, KOCATURK, OZGUR · 2020 to 2023
$1.6M
Safe Ultrasonic Transmission Lines for MRI CathetersR21EB019098 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI DEGERTEKIN, F. LEVENT · 2014 to 2015
$420k
Intramural NIH HHS ZIA HL006039NIBIB NIH HHS R01 EB029331NIBIB NIH HHS R21 EB019098
6 · The paper itself

Abstract

purposeThis work aims to demonstrate the use of an "active" acousto-optic marker with enhanced visibility and reduced radiofrequency (RF) -induced heating for interventional MRI.

methodsThe acousto-optic marker was fabricated using bulk piezoelectric crystal and π-phase shifted fiber Bragg grating (FBGs) and coupled to a distal receiver coil on an 8F catheter. The received MR signal is transmitted over an optical fiber to mitigate RF-induced heating. A photodetector converts the optical signal into electrical signal, which is used as the input signal to the MRI receiver plug. Acousto-optic markers were characterized in phantom studies. RF-induced heating risk was evaluated according to ASTM 2182 standard. In vivo real-time tracking capability was tested in an animal model under a 0.55T scanner.

resultsSignal-to-noise ratio (SNR) levels suitable for real-time tracking were obtained by using high sensitivity FBG and piezoelectric transducer with resonance matched to Larmor frequency. Single and multiple marker coils integrated to 8F catheters were readout for position and orientation tracking by a single acousto-optic sensor. RF-induced heating was significantly reduced compared to a coax cable connected reference marker. Real-time distal tip tracking of an active device was demonstrated in an animal model with a standard real-time cardiac MR sequence.

conclusionAcousto-optic markers provide sufficient SNR with a simple structure for real-time device tracking. RF-induced heating is significantly reduced compared to conventional active markers. Also, multiple RF receiver coils connected on an acousto-optic modulator can be used on a single catheter for determining catheter orientation and shape.

Indexed as

Magnetic Resonance ImagingMagnetic Resonance Imaging, InterventionalAnimalsCathetersEquipment DesignPhantoms, Imagingacousto-optic modulationactive devicescatheterfiber optic sensorinterventional MRIreal-time tracking

Identifiers

PMID33347642
PMCPMC7902374
OpenAlexW3113789664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.