Evidence map›Paper›PMID 33347630›Full record

ArticleMuscle & nerve2021

Muscle fiber size in healthy children and adults in relation to sex and fiber types.

Mona E Esbjörnsson, Monica S Dahlström, Jan W Gierup, Eva Ch Jansson

Abstract read
In one paragraph

Article in Muscle & nerve, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Assessment and rehabilitation of tongue motor skills with myofunctional therapy in obstructive sleep apnea: a systematic review and meta-analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Pooled it
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  9. A question of rate? Girl-women differences in motor unit firing rate.European journal of applied physiology · 2026
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  11. Review
  12. Children'sEuropean journal of applied physiology · 2025
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Optimization of post-activation potentiation in girls and women.European journal of applied physiology · 2024
    Article
  18. Article
  19. Sexual dimorphisms in skeletal muscle: current concepts and research horizons.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mona E EsbjörnssonDivision of Clinical Physiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Monica S DahlströmRetired, Sollentuna, Sweden.
Jan W GierupRetired, Lidingö, Sweden.
Eva Ch JanssonDivision of Clinical Physiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn adult males, cross-sectional area (CSA) for type II muscle fibers is generally larger than for type I fibers. In this cross-sectional study the aim was to compare sex-related CSAs of various muscle fiber types during childhood-to-adulthood transition.

methodsPercutaneous biopsy samples were obtained from vastus lateralis in 10-y-old children (10 males and 5 females) and in young adults (9 males and 7 females). Fiber types were classified by myofibrillar ATPase and CSAs from NADH-dehydrogenase staining.

resultsType IIA were larger than type I fibers in adult males, but not in adult females or children (age x sex x fiber type, P < .002). When including all participants, body weight and sex explained 78% of the variation in type IIA CSA but only body weight contributed for type I.

conclusionsSex-specific patterns in CSA of the muscle fiber types appears to develop during the transition from childhood to adulthood.

Indexed as

Sex FactorsAdolescentAdultAge FactorsBody WeightChildCross-Sectional StudiesFemaleHumansMaleMuscle Fibers, Fast-TwitchMuscle Fibers, SkeletalMuscle, SkeletalQuadriceps MuscleYoung Adultagecross-sectional areahumanmuscle biopsyvastus lateralis

Identifiers

PMID33347630
PMCPMC8048954

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.