Evidence map›Paper›PMID 33347578›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2020

Estimating the Economic Impact of Respiratory Syncytial Virus and Other Acute Respiratory Infections Among Infants Receiving Care at a Referral Hospital in Malawi.

Ranju Baral, Ivan Mambule, Elisabeth Vodicka, Neil French, Dean Everett, Clint Pecenka, Naor Bar-Zeev

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ranju BaralCenter for Vaccine Innovation and Access, PATH, Seattle, Washington, USA.
Ivan MambuleClinical Research Programme, Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Elisabeth VodickaCenter for Vaccine Innovation and Access, PATH, Seattle, Washington, USA.
Neil FrenchClinical Research Programme, Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Dean EverettClinical Research Programme, Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Clint PecenkaCenter for Vaccine Innovation and Access, PATH, Seattle, Washington, USA.
Naor Bar-ZeevClinical Research Programme, Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Program for Appropriate Technology in Health · USUniversity of Liverpool · GBJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is a leading cause of respiratory illness among infants globally, yet economic burden data are scant, especially in low-income countries.

methodsWe collected data from 426 infants enrolled in the Queen Elizabeth Central Hospital respiratory disease surveillance platform to estimate the household and health system costs of managing RSV and other respiratory pathogens in Malawian infants. Total household cost per illness episode, including direct and indirect costs and lost income, was reported by parents/guardians at the initial visit and 6 weeks post discharge. The total cost to the health system was based on patient charts and hospital expenditures. All-cause acute respiratory infections (ARIs) and RSV costs for inpatient and outpatients are presented separately. All costs are in the 2018 US Dollar.

resultsThe mean costs per RSV episode were $62.26 (95% confidence interval [CI]: $50.87-$73.66) and $12.51 (95% CI: $8.24-$16.79) for inpatient and outpatient cases, respectively. The mean cost per episode for all-cause ARIs was slightly higher among inpatients at $69.93 (95% CI: $63.06-$76.81) but slightly lower for outpatients at $10.17 (95% CI: $8.78-$11.57). Household costs accounted for roughly 20% of the total cost per episode. For the lowest-income families, household cost per inpatient RSV episode was about 32% of total monthly household income.

conclusionsAmong infants receiving care at a referral hospital in Malawi, the cost per episode in which RSV was detected is comparable to that of other episodes of respiratory illnesses where RSV was not detected. Estimates generated in this study can be used to evaluate the economic and financial impact of RSV and acute respiratory illness preventive interventions in Malawi.

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsAftercareCost of IllnessHospitalizationHospitalsHumansInfantMalawiPatient DischargeReferral and Consultationacute respiratory infections (ARIs)cost per episodecostshousehold costsrespiratory syncytial virus (RSV)

Identifiers

PMID33347578
PMCPMC7864144
OpenAlexW3113868438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.