Evidence map›Paper›PMID 33347312›Full record

ArticleChemical research in toxicology2021

Deep Graph Learning with Property Augmentation for Predicting Drug-Induced Liver Injury.

Hehuan Ma, Weizhi An, Yuhong Wang, Hongmao Sun, Ruili Huang, Junzhou Huang

Open access · greenAbstract read
In one paragraph

Article in Chemical research in toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  8. In silico modeling-based new alternative methods to predict drug and herb-induced liver injury: A review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023
    Review
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  14. Computational toxicology (Amsterdam, Netherlands) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hehuan MaDepartment of Computer Science, University of Texas at Arlington, Arlington, Texas 76013, United States.ORCID 0000-0002-5971-0053
Weizhi AnDepartment of Computer Science, University of Texas at Arlington, Arlington, Texas 76013, United States.
Yuhong WangNational Center for Advancing Translating Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Hongmao SunNational Center for Advancing Translating Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Ruili HuangNational Center for Advancing Translating Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Junzhou HuangDepartment of Computer Science, University of Texas at Arlington, Arlington, Texas 76013, United States.
National Institutes of Health · USThe University of Texas at Arlington · US

Funding

Toxicology in the 21st Century Program (Tox21) - Computational ToxicologyZIATR000040 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI HUANG, RUILI · 2016 to 2025
$3.5M
Intramural NIH HHS Z99 TR999999
6 · The paper itself

Abstract

Drug-induced liver injury (DILI) is a crucial factor in determining the qualification of potential drugs. However, the DILI property is excessively difficult to obtain due to the complex testing process. Consequently, an

Indexed as

Chemical and Drug Induced Liver InjuryDeep LearningModels, ChemicalHumansMolecular StructurePharmaceutical PreparationsPharmaceutical Preparations

Identifiers

PMID33347312
PMCPMC9887540
OpenAlexW3114373613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.