Evidence map›Paper›PMID 33346872›Full record

ReviewDer Pathologe2021

[Interdisciplinary S2k guidelines on the diagnosis and treatment of vaginal carcinoma and its precursors-recommendations on surgical pathology for histopathological workup, diagnostics, and reporting].

Lars-Christian Horn, Anne Kathrin Höhn, Monika Hampl, Grit Mehlhorn, Markus Follmann, Hans-Georg Schnürch, Kommission zur Erstellung der S2k-Leitlinie Vaginalkarzinom

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Pathologe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. 2020 WHO Classification of Female Genital Tumors.Geburtshilfe und Frauenheilkunde · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Lars-Christian HornInstitut für Pathologie, Abteilung Mamma‑, Gynäko- & Perinatalpathologie, Universitätsklinikum Leipzig AöR, Liebigstraße 26, 04103, Leipzig, Deutschland. hornl@medizin.uni-leipzig.de.
Anne Kathrin HöhnInstitut für Pathologie, Abteilung Mamma‑, Gynäko- & Perinatalpathologie, Universitätsklinikum Leipzig AöR, Liebigstraße 26, 04103, Leipzig, Deutschland.
Monika HamplUniversitätsfrauenklinik, Heinrich-Heine-Universität, Düsseldorf, Deutschland.
Grit MehlhornFrauenarztpraxis Erlangen, Erlangen, Deutschland.
Markus FollmannDeutsche Krebsgesellschaft, Berlin, Deutschland.
Hans-Georg SchnürchLukaskrankenhaus Neuss, Kaarst, Deutschland.
Kommission zur Erstellung der S2k-Leitlinie Vaginalkarzinom
Düsseldorf University Hospital · DEGerman Cancer Society · DEUniversity Hospital Leipzig · DELukaskrankenhaus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary vaginal carcinoma is rare. There are two pathogenetic pathways, one associated with HPV high-risk infection and another one with inactivation of p53. Vaginal Paget's disease is rare and mostly associated with vulvar disease or represents intravaginal spread of associated locoregional cancer. Diagnostic vaginal biopsies should be examined by step sections on H&E. Sentinel lymph nodes should be processed completely using ultrastaging. Morphology-based prognostic factors with good clinical evidence are tumour stage and lymph node status. Molecular markers are not currently relevant for treatment decision and prognosis.

Indexed as

Carcinoma in SituPathology, SurgicalVaginal NeoplasmsVulvar NeoplasmsFemaleHumansNeoplasm StagingPrognosisSentinel Lymph Node BiopsyCancerDiagnosticGuidelinesHistopathologyPrognosisStagingTreatmentVaginaVaINWHOWorkup

Identifiers

PMID33346872
OpenAlexW3114462740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.