Evidence map›Paper›PMID 33346072›Full record

ArticleDiabetes research and clinical practice2021

Widespread sensory neuropathy in diabetic patients hospitalized with severe COVID-19 infection.

Ariel Odriozola, Lucía Ortega, Lidia Martinez, Samantha Odriozola, Ainhoa Torrens, David Corroleu, Silvia Martínez, Meritxell Ponce, Yolanda Meije, Mercedes Presas and 3 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Diabetes research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Prognosis of patients with coronavirus disease with or without anosmia: A systematic review.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2025
    Review
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  7. Article
  8. Review
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  10. Update on Corneal Confocal Microscopy Imaging.Diagnostics (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. COVID-19 and the hidden threat of diabetic microvascular complications.Therapeutic advances in endocrinology and metabolism · 2022
    Review
  16. Observational
  17. Article
  18. Neuropathy in COVID-19 associated with dysbiosis-related inflammation.Turkish journal of biology = Turk biyoloji dergisi · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Ariel OdriozolaHospital of Barcelona SCIAS, Barcelona, Spain. Electronic address: ariel_16oo@hotmail.com.
Lucía OrtegaHospital of Barcelona SCIAS, Barcelona, Spain.
Lidia MartinezHospital of Barcelona SCIAS, Barcelona, Spain.
Samantha OdriozolaPhi Med Europe SL., Barcelona, Spain.
Ainhoa TorrensHospital of Barcelona SCIAS, Barcelona, Spain.
David CorroleuHospital of Barcelona SCIAS, Barcelona, Spain.
Silvia MartínezHospital of Barcelona SCIAS, Barcelona, Spain.
Meritxell PonceHospital of Barcelona SCIAS, Barcelona, Spain.
Yolanda MeijeHospital of Barcelona SCIAS, Barcelona, Spain.
Mercedes PresasHospital of Barcelona SCIAS, Barcelona, Spain.
Alejandra DuarteHospital of Barcelona SCIAS, Barcelona, Spain.
M Belén OdriozolaPhi Med Europe SL., Barcelona, Spain.
Rayaz A MalikDepartment of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar.
Hospital de Nens de Barcelona · ESWeill Cornell Medical College in Qatar · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo characterize the distribution and severity of sensory neuropathy using a portable quantitative sensory testing (QST) device in diabetic patients (DM) hospitalized with severe COVID-19 infection.

methodsFour patients with diabetes and severe SARS-CoV-2 requiring non-invasive ventilation for a protracted duration underwent clinical, laboratory and radiologic assessment and detailed evaluation of neuropathic symptoms, neurological assessment, QST on the dorsum of the foot and face using NerveCheck Master with assessment of taste and smell.

resultsAll four subjects developed neuropathic symptoms characterized by numbness in the feet with preserved reflexes. QST confirmed symmetrical abnormality of vibration and thermal thresholds in both lower limbs in all patients and an abnormal heat pain threshold on the face of two patients and altered taste and smell.

conclusionsSevere COVID-19 infection with hypoxemia is associated with neuropathic symptoms and widespread sensory dysfunction in patients with DM.

Indexed as

SARS-CoV-2AgedComorbidityCOVID-19Diabetes MellitusDiabetic NeuropathiesFemaleHumansMaleMiddle AgedNeurologic ExaminationSensation DisordersSensory ThresholdsCOVID-19DiabetesDiagnostic deviceNerveCheckQuantitative sensory testingSensory neuropathy

Identifiers

PMID33346072
PMCPMC7746125
OpenAlexW3113118526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.