Evidence map›Paper›PMID 33345593›Full record

ArticleAIDS care2021

"You are not alone": a qualitative study to explore barriers to ART initiation and implications for a proposed community-based youth treatment club among young adults newly diagnosed with HIV in South Africa.

Maria F Nardell, Yeonsoo Sara Lee, Elzette Rousseau, Robin Julies, Portia Klaas, Prisca Vundhla, Lisa Butler, Ingrid V Bassett, Claude A Mellins, Linda-Gail Bekker and 1 more

Abstract read
In one paragraph

Article in AIDS care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Why Are They Leaving? Factors Associated With Attrition After Testing Among Young South Africans Recently Diagnosed With HIV: An Observational Study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria F NardellConnors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-1186-3595
Yeonsoo Sara LeeDivision of Women's Health, Brigham and Women's Hospital, Boston, MA, USA.
Elzette RousseauThe Desmond Tutu Health Foundation, University of Cape Town, Cape Town, Republic of South Africa.
Robin JuliesThe Desmond Tutu Health Foundation, University of Cape Town, Cape Town, Republic of South Africa.
Portia KlaasThe Desmond Tutu Health Foundation, University of Cape Town, Cape Town, Republic of South Africa.
Prisca VundhlaThe Desmond Tutu Health Foundation, University of Cape Town, Cape Town, Republic of South Africa.
Lisa ButlerInstitute for Collaboration on Health, Intervention and Policy, University of Connecticut, Storrs, CT, USA.
Ingrid V BassettHarvard Medical School, Boston, MA, USA.
Claude A MellinsHIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University, New York, NY, USA.
Linda-Gail BekkerThe Desmond Tutu Health Foundation, University of Cape Town, Cape Town, Republic of South Africa.ORCID 0000-0002-0755-4386
Ingrid T KatzHarvard Medical School, Boston, MA, USA.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ARTHUR Y KIM · 2004 to 2026
$94.4M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Mentoring in patient-oriented research on HIV prevention in the US and South AfricaK24AI141036 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Ingrid Valerie Bassett · 2019 to 2026
$1.1M
Standing Tall - A Pilot Randomized Controlled Trial of a Community-Based Intervention to Improve Health Outcomes for Newly Diagnosed HIV-Positive Young Adults in South AfricaR34MH114897 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI KATZ, INGRID T. · 2018 to 2021
$925k
NIAID NIH HHS K24 AI141036NIAID NIH HHS P30 AI060354NIAID NIH HHS T32 AI007433NIMH NIH HHS R34 MH114897
6 · The paper itself

Abstract

In South Africa, despite universal antiretroviral therapy (ART) availability, 60% of persons living with HIV (PLWH) ages 15-24 are not on treatment. This qualitative study aimed to identify barriers to ART initiation and the implications for a proposed community-based Youth Treatment Club to improve ART initiation for young PLWH in limited-resource, high HIV-prevalence communities in Cape Town, South Africa. Recruiting participants at community testing sites from 2018 to 2019, we conducted semi-structured interviews, informed by Social Action Theory (SAT), with 20 young adults, ages 18- to 24-years-old, newly diagnosed with HIV, along with 10 healthcare providers. Through systematic qualitative analysis, we found that young PLWH face barriers to treatment initiation in three SAT domains: (1) stigmatizing social norms (social regulation processes); (2) challenges coping with a new diagnosis (self-regulation processes); and (3) anticipated stigma in the clinic environment (contextual factors). Participants shared that a proposed community-based Youth Treatment Club for newly diagnosed youth would be an acceptable strategy to promote ART initiation. They emphasized that it should include supportive peers, trained facilitator support for counseling and education, and a youth-friendly environment.

Indexed as

HIV InfectionsAdolescentAdultCounselingHumansQualitative ResearchSocial StigmaSouth AfricaYoung Adultadolescentsantiretroviral treatmentcopingHIVSouth Africa

Identifiers

PMID33345593
PMCPMC8215080

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.