ReviewExperimental physiology2021
A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies.
Review in Experimental physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Is resting muscle sympathetic nerve activity related to peripheral or cerebrovascular haemodynamics at high altitude? A retrospective analysis.Experimental physiology · 2026Article
- High-Altitude Residence, Blood Biomarkers, and Chronic Disease Risk in Middle-Aged and Older Chinese Adults.Healthcare (Basel, Switzerland) · 2026Article
- Human adaptation to high-altitude: A contemporary comparison of the oxygen cascade in Andean, Tibetan and Ethiopian highlanders.Experimental physiology · 2026Review
- Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans.Experimental physiology · 2026Article
- Physiological responses to short-term high-altitude acclimatization: Insights from predictive modeling approaches.Physiological reports · 2026Article
- Review
- Evolved changes in reflex control of the cardiovascular system in deer mice native to high altitude.The Journal of experimental biology · 2025Article
- Improved oxygen saturation and acclimatization with bacteriotherapy at high altitude.iScience · 2025Article
- Cerebral homeostasis and orthostatic responses in residents of the highest city in the world.Scientific reports · 2024Article
- Knowledge, attitude, and practice of atrial fibrillation in high altitude areas.Frontiers in public health · 2024Article
- Tibetans exhibit lower hemoglobin concentration and decreased heart response to hypoxia during poikilocapnia at intermediate altitude relative to Han Chinese.Frontiers in physiology · 2024Article
- Attenuated cardiac autonomic function in humans with high-affinity hemoglobin and compensatory polycythemia.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- The role of (pro)renin receptor and its soluble form in cardiovascular diseases.Frontiers in cardiovascular medicine · 2023Review
- A change of heart: Mechanisms of cardiac adaptation to acute and chronic hypoxia.The Journal of physiology · 2022Article
- High altitude is associated with pTau deposition, neuroinflammation, and myelin loss.Scientific reports · 2022Article
- Changes in cardiac function following a speed ascent to the top of Europe at 4808 m.European journal of applied physiology · 2022Article
- Duration at high altitude influences the onset of arrhythmogenesis during apnea.European journal of applied physiology · 2022Article
- Adrenergic control of the cardiovascular system in deer mice native to high altitude.Current research in physiology · 2022Article
- Acute Moderate Hypoxia Reduces One-Legged Cycling Performance Despite Compensatory Increase in Peak Cardiac Output: A Pilot Study.International journal of environmental research and public health · 2021Article
- A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies.Experimental physiology · 2021Review
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
NEW
findingsWhat is the topic of the review? Sympathoexcitation and sympathetic control of blood pressure at high altitude. What advances does it highlight? Sustained sympathoexcitation is fundamental to integrative control of blood pressure in humans exposed to chronic hypoxia. The largest gaps in current knowledge are in understanding the complex mechanisms by which central sympathetic outflow is regulated at high altitude. ABSTRACT: High altitude (HA) hypoxia is a potent activator of the sympathetic nervous system, eliciting increases in sympathetic vasomotor activity. Microneurographic evidence of HA sympathoexcitation dates back to the late 20th century, yet only recently have the characteristics and underpinning mechanisms been explored in detail. This review summarises recent findings and highlights the importance of HA sympathoexcitation for the regulation of blood pressure in lowlanders and indigenous highlanders. In addition, this review identifies gaps in our knowledge and corresponding avenues for future study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.