ArticleCerebral cortex (New York, N.Y. : 1991)2021
Transdiagnostic, Connectome-Based Prediction of Memory Constructs Across Psychiatric Disorders.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Parcellation-based tractographic modeling of the salience network through meta-analysis.Brain and behavior · 2022Pooled it
- Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.Dialogues in clinical neuroscience · 2027Trial
- Connectome-based substrates of emotional N-back performance in the adolescent brain cognitive development study.Developmental cognitive neuroscience · 2026Article
- State-Specific Segmental Abnormalities of White Matter Structure and Function in Pediatric Bipolar Disorders.Bipolar disorders · 2026Article
- Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting.Nature communications · 2026Article
- Untangling the tangled relationship between cognitive and psychological comorbidities in epilepsy: Bidirectionality and mediation.Epilepsia · 2025Article
- Transdiagnostic connectome-based predictive modeling of many behavioral phenotypes reveals brain network mediators of clinical-cognitive relationships.bioRxiv : the preprint server for biology · 2025Article
- Abnormalities in cognitive-related functional connectivity can be used to identify patients with schizophrenia and individuals in clinical high-risk.BMC psychiatry · 2025Article
- Brain functional connectivity and anatomical features as predictors of cognitive behavioral therapy outcome for anxiety in youths.Psychological medicine · 2025Article
- Transdiagnostic Connectome-Based Prediction of Response Inhibition.Human brain mapping · 2025Article
- Connectome-based fingerprinting: reproducibility, precision, and behavioral prediction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Quantitative Expression of Latent Disease Factors in Individuals Associated with Psychopathology Dimensions and Treatment Response.Neuroscience bulletin · 2024Article
- Brain-phenotype predictions can survive across diverse real-world data.bioRxiv : the preprint server for biology · 2024Article
- Rescuing missing data in connectome-based predictive modeling.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Linking the neural signature of response time variability to Alzheimer's disease pathology and cognitive functioning.Network neuroscience (Cambridge, Mass.) · 2024Article
- The effects of data leakage on connectome-based machine learning models.bioRxiv : the preprint server for biology · 2023Article
- Functional connectomes of akinetic-rigid and tremor within drug-naïve Parkinson's disease.CNS neuroscience & therapeutics · 2023Article
- Cross-attractor modeling of resting-state functional connectivity in psychiatric disorders.NeuroImage · 2023Article
- Altered Brain Dynamics Across Bipolar Disorder and Schizophrenia During Rest and Task Switching Revealed by Overlapping Brain States.Biological psychiatry · 2023Article
- Brain-Based Predictions of Psychiatric Illness-Linked Behaviors Across the Sexes.Biological psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Memory deficits are observed in a range of psychiatric disorders, but it is unclear whether memory deficits arise from a shared brain correlate across disorders or from various dysfunctions unique to each disorder. Connectome-based predictive modeling is a computational method that captures individual differences in functional connectomes associated with behavioral phenotypes such as memory. We used publicly available task-based functional MRI data from patients with schizophrenia (n = 33), bipolar disorder (n = 34), attention deficit hyper-activity disorder (n = 32), and healthy controls (n = 73) to model the macroscale brain networks associated with working, short- and long-term memory. First, we use 10-fold and leave-group-out analyses to demonstrate that the same macroscale brain networks subserve memory across diagnostic groups and that individual differences in memory performance are related to individual differences within networks distributed throughout the brain, including the subcortex, default mode network, limbic network, and cerebellum. Next, we show that diagnostic groups are associated with significant differences in whole-brain functional connectivity that are distinct from the predictive models of memory. Finally, we show that models trained on the transdiagnostic sample generalize to novel, healthy participants (n = 515) from the Human Connectome Project. These results suggest that despite significant differences in whole-brain patterns of functional connectivity between diagnostic groups, the core macroscale brain networks that subserve memory are shared.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.