Evidence map›Paper›PMID 33345188›Full record

ArticleNAR cancer2020

Unique

HoJoon Lee, Ahmed Shuaibi, John M Bell, Dmitri S Pavlichin, Hanlee P Ji

Open access · goldAbstract read
In one paragraph

Article in NAR cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. A survey of k-mer methods and applications in bioinformatics.Computational and structural biotechnology journal · 2024
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

HoJoon LeeDivision of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Ahmed ShuaibiDivision of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
John M BellStanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA.
Dmitri S PavlichinDivision of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Hanlee P JiDivision of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-3772-3424
Stanford University · US

Funding

K-mer indexing for pan-genome reference annotationU01HG010963 · NHGRI · STANFORD UNIVERSITY · PI JI, HANLEE P, WEISSMAN, TSACHY · 2020 to 2023
$1.3M
NHGRI NIH HHS U01 HG010963
6 · The paper itself

Abstract

Cancer genome sequencing has led to important discoveries such as the identification of cancer genes. However, challenges remain in the analysis of cancer genome sequencing. One significant issue is that mutations identified by multiple variant callers are frequently discordant even when using the same genome sequencing data. For insertion and deletion mutations, oftentimes there is no agreement among different callers. Identifying somatic mutations involves read mapping and variant calling, a complicated process that uses many parameters and model tuning. To validate the identification of true mutations, we developed a method using

Identifiers

PMID33345188
PMCPMC7727745
OpenAlexW3111496628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.