ArticleBrain communications2020
The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages.
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Article in Brain communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
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- Is the Relationship Between Cardiovascular Disease and Alzheimer's Disease Genetic? A Scoping Review.Genes · 2024Article
- Association of Neurotrophic Factors at Midlife With In Vivo Measures of β-Amyloid and Tau Burden 15 Years Later in Dementia-Free Adults.Neurology · 2024Article
- A genetic exploration of the relationship between Posttraumatic Stress Disorder and cardiovascular diseases.medRxiv : the preprint server for health sciences · 2024Article
- Poor sleep versus exercise: A duel to decide whether pain resolves or persists after injury.Brain, behavior, & immunity - health · 2024Article
- Genetic associations and potential mediators between psychiatric disorders and irritable bowel syndrome: a Mendelian randomization study with mediation analysis.Frontiers in psychiatry · 2024Article
- Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases.Frontiers in neurology · 2024Review
- Deciphering the Effect of Different Genetic Variants on Hippocampal Subfield Volumes in the General Population.International journal of molecular sciences · 2023Article
- Sedentary behavior, brain-derived neurotrophic factor and brain structure in midlife: A longitudinal brain MRI sub-study of the coronary artery risk development in young adults study.Frontiers in dementia · 2023Article
- Review
- Accelerometer-Measured, Habitual Physical Activity and Circulating Brain-Derived Neurotrophic Factor: A Cross-Sectional Study.Journal of Alzheimer's disease : JAD · 2022Article
- Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis.Cellular and molecular life sciences : CMLS · 2021Article
Corrections and comments
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Authors and funding
18 authors at 10 institutions in 5 countries.
Shuo LiDepartment of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.
Galit WeinsteinSchool of Public Health, University of Haifa, Haifa 3498838, Israel.ORCID 0000-0002-1316-4448
Habil ZareDepartment of Cell Systems and Anatomy, University of Texas Health San Antonio, San Antonio, TX, USA.
Alexander TeumerInstitute for Community Medicine, University Medicine Greifswald, Germany.
Uwe VölkerDZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.
Nele FriedrichInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany.
Maria J KnolDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, 3000 CA, The Netherlands.ORCID 0000-0002-3597-1531
Claudia L SatizabalGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, 78229 TX, USA.
Vladislav A PetyukPacific Northwest National Laboratory, Richland, WA 99354, USA.ORCID 0000-0003-4076-151X
Hieab H H AdamsDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, 3000 CA, The Netherlands.
Lenore J LaunerDepartment of Health and Human Services, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
David A BennettDepartment of Neurology, Rush University Medical Center, Chicago, IL 60612, USA.
Philip L De JagerDepartment of Neurology, Center for Translational and Computational Neuroimmunology, Columbia University Medical Center, New York, NY 10032, USA.
Hans J GrabeDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Germany.
M Arfan IkramDepartment of Clinical Genetics, Erasmus University Medical Center, Rotterdam, 3000 CA, The Netherlands.
Vilmundur GudnasonFaculty of Medicine, School of Health Sciences, University of Iceland, 101 Reykjavik, Iceland.
Qiong YangDepartment of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.
Sudha SeshadriGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, 78229 TX, USA.
Boston University · USUniversitätsmedizin Greifswald · DEErasmus MC · NLBroad Institute · USNational Institutes of Health · USPacific Northwest National Laboratory · USRush University Medical Center · USThe University of Texas Health Science Center at San Antonio · USUniversity of Haifa · ILUniversity of Iceland · IS
Funding
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 1991 to 2020
$49.1MEPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3MFRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN · 2019 to 2024
$29.8MPRECURSORS OF STROKE INCIDENCE AND PROGNOSISR01NS017950 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Hugo Javier Aparicio, Jose Rafael Romero · 1985 to 2026
$22.9MRISK FACTORS, PATHOLOGY, AND CLINICAL EXPRESSIONS OF ADR01AG015819 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1998 to 2024
$21.4MMulti-omic network-directed proteoform discovery, dissection and functional validation to prioritize novel AD therapeutic targetsU01AG061356 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BENNETT, DAVID ALAN, DE JAGER, PHILIP L · 2018 to 2022
$13.7MPathway discovery, validation and compound identification for Alzheimer's disease - SupplementU01AG046152 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BENNETT, DAVID ALAN, DE JAGER, PHILIP L · 2013 to 2017
$13.6MTemporal Trends, Novel Imaging and Molecular Characterization of Preclinical and Clinical Alzheimer's Disease in the Framingham CohortsR01AG054076 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DECARLI, CHARLES, SESHADRI, SUDHA · 2016 to 2020
$12.3MMRI Evaluation Of Acute Cardiovascular DiseaseZ01HL004607 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI ARAI, ANDREW E · 1999 to 2008
$8.0MCognitively Healthy Nonagenarians in the Cross Cohort Collaboration (CCC)RF1AG059421 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SESHADRI, SUDHA · 2018 to 2018
$6.1MCognitively Healthy Nonagenarians in the Cross Cohort Collaboration (CCC)R01AG059421 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Stephanie Anne-Carine Debette, Carole Dufouil · 2026 to 2026
$4.7MPreclinical AD: Correlates of Amyloid, Tau PET and fcMRI in Framingham Gen 3 Young AdultsR01AG049607 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SESHADRI, SUDHA · 2015 to 2019
$3.1MIntramural NIH HHS Z01 HL004607NHLBI NIH HHS 75N92019D00031NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS N01 HC025195NHLBI NIH HHS N02 HL064278NIA NIH HHS N01 AG012100NIA NIH HHS P30 AG010161NIA NIH HHS R01 AG015819NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG031287NIA NIH HHS R01 AG049607NIA NIH HHS R01 AG054076NIA NIH HHS R01 AG059421NIA NIH HHS RF1 AG059421NIA NIH HHS U01 AG046152NIA NIH HHS U01 AG049505NIA NIH HHS U01 AG052409NIA NIH HHS U01 AG061356NINDS NIH HHS R01 NS017950
Abstract
Brain-derived neurotrophic factor (BDNF) plays an important role in brain development and function. Substantial amounts of BDNF are present in peripheral blood, and may serve as biomarkers for Alzheimer's disease incidence as well as targets for intervention to reduce Alzheimer's disease risk. With the exception of the genetic polymorphism in the
Indexed as
Alzheimer’s diseasebrain agingbrain-derived neurotrophic factorgenome-wide association study
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