Evidence map›Paper›PMID 33344919›Full record

ArticleiScience2020

MR1-Restricted T Cells with MAIT-like Characteristics Are Functionally Conserved in the Pteropid Bat

Edwin Leeansyah, Ying Ying Hey, Wan Rong Sia, Justin Han Jia Ng, Muhammad Yaaseen Gulam, Caroline Boulouis, Feng Zhu, Matae Ahn, Jeffrey Y W Mak, David P Fairlie and 3 more

Abstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. MAIT cells: Conserved watchers on the wall.The Journal of experimental medicine · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. MAIT cells in liver inflammation and fibrosis.Seminars in immunopathology · 2022
    Review
  14. Review
  15. Frontiers in immunology · 2022
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Edwin LeeansyahProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Ying Ying HeyProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Wan Rong SiaProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Justin Han Jia NgProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Muhammad Yaaseen GulamProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Caroline BoulouisCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, 14183 Stockholm, Sweden.
Feng ZhuProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Matae AhnProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Jeffrey Y W MakDivision of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
David P FairlieDivision of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Andrea Lay Hoon KwaProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.
Johan K SandbergCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, 14183 Stockholm, Sweden.
Lin-Fa WangProgramme in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore 169857, Singapore.

Funding

Intestinal MAIT Cells in HIV InfectionR01DK108350 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PAQUIN-PROULX, DOMINIC, SANDBERG, JOHAN K · 2015 to 2019
$2.5M
NIDDK NIH HHS R01 DK108350
6 · The paper itself

Abstract

Bats are reservoirs for a large number of viruses which have potential to cause major human disease outbreaks, including the current coronavirus disease 2019 (COVID-19) pandemic. Major efforts are underway to understand bat immune response to viruses, whereas much less is known about their immune responses to bacteria. In this study, MR1-restricted T (MR1T) cells were detected through the use of MR1 tetramers in circulation and tissues of

Indexed as

Biological SciencesComponents of the Immune SystemsImmunology

Identifiers

PMID33344919
PMCPMC7736909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.