Evidence map›Paper›PMID 33344716›Full record

ArticleNeurobiology of stress2020

Validation of an Electrochemical Sensor to Detect Cortisol Responses to the Trier Social Stress Test.

Guido G Urizar, Hugo Sanchez Hernandez, Jessica Rayo, Shekhar Bhansali

Abstract read
In one paragraph

Article in Neurobiology of stress, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guido G UrizarDepartment of Psychology, California State University, Long Beach, 1250 Bellflower Blvd, Long Beach, CA, 90840-0901, USA.
Hugo Sanchez HernandezDepartment of Psychology, California State University, Long Beach, 1250 Bellflower Blvd, Long Beach, CA, 90840-0901, USA.
Jessica RayoDepartment of Psychology, California State University, Long Beach, 1250 Bellflower Blvd, Long Beach, CA, 90840-0901, USA.
Shekhar BhansaliDepartment of Electrical & Computer Engineering, Florida International University, 10555 West Flagler St. EC 3900, Miami, FL, 33174, USA.

Funding

CSULB Building Biomedical Research Program: Overall ComponentUL1GM118979 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI CHUN, CHI-AH, DILLON, JESSE · 2015 to 2023
$20.7M
CSULB Building Biomedical Research Program: Student Training CoreTL4GM118980 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI CHUN, CHI-AH, DILLON, JESSE · 2015 to 2023
$12.3M
CSULB Building Biomedical Research Program: Research Enrichment CoreRL5GM118978 · NIGMS · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI CHUN, CHI-AH, DILLON, JESSE · 2015 to 2023
$7.3M
Impact of a Cognitive Behavioral Stress Management Intervention on Cortisol RegulSC2HD068878 · NICHD · CALIFORNIA STATE UNIVERSITY LONG BEACH · PI URIZAR, GUIDO G. · 2010 to 2012
$368k
NICHD NIH HHS SC2 HD068878NIGMS NIH HHS RL5 GM118978NIGMS NIH HHS TL4 GM118980NIGMS NIH HHS UL1 GM118979
6 · The paper itself

Abstract

Recent advances in sensor technology allow for the detection of salivary cortisol levels in real-time, yet studies are needed to test their reliability in clinically at-risk populations. This study examined whether a new electrochemical sensor reliably detected cortisol patterns, compared to a conventional immunoassay test (i.e., ELISA), among women and men with low and high depressive symptoms who participated in the Trier Social Stress Test (TSST; a laboratory-based stressor). Results demonstrated that women and those with high depressive symptoms showed lower cortisol levels throughout the TSST overall compared to men and those with low depressive symptoms. The cortisol sensor was highly reliable when compared to the ELISA immunoassay in detecting cortisol responses to the TSST for both women and men and for participants with low and high depressive symptoms. These results suggest that the sensor is a promising tool for assessing real-time cortisol responses to laboratory stressors in at-risk populations.

Indexed as

CortisolDepressionGenderSensorTSST

Identifiers

PMID33344716
PMCPMC7739168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.