ArticleOrthopaedic journal of sports medicine2020
Dose and Recovery Response of Patellofemoral Cartilage Deformations to Running.
Article in Orthopaedic journal of sports medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Immediate and Delayed Effects of Joint Loading Activities on Knee and Hip Cartilage: A Systematic Review and Meta-analysis.Sports medicine - open · 2023Pooled it
- The Influence of Running on Lower Limb Cartilage: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- A deep learning-based approach for measuring patellar cartilage deformations from knee MR images.Journal of biomechanics · 2025Article
- Tibiofemoral cartilage strain and recovery following a 3-mile run measured using deep learning segmentation of bone and cartilage.Osteoarthritis and cartilage open · 2025Article
- Baseline-to-loaded changes in regional tibial cartilage thickness, T1ρ and T2: Utilization of an MRI compatible loading device.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Morphologic Response in Femoral Cartilage During and After 40-Minute Treadmill Running.Journal of athletic training · 2024Article
- Effects of long-term running on the structure and biochemical composition of knee cartilage in males: a cross-sectional study.Quantitative imaging in medicine and surgery · 2024Article
- Influence of running on femoroacetabular joint bone-to-bone distances.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Auto-segmentation of the tibia and femur from knee MR images via deep learning and its application to cartilage strain and recovery.Journal of biomechanics · 2023Article
- Design and validation of a semi-automatic bone segmentation algorithm from MRI to improve research efficiency.Scientific reports · 2022Article
- Obesity impacts the mechanical response and biochemical composition of patellofemoral cartilage: An in vivo, MRI-based investigation.Journal of biomechanics · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundRunning is a common recreational activity that provides many health benefits. However, it remains unclear how patellofemoral cartilage is affected by varied running distances and how long it takes the cartilage to recover to its baseline state after exercise. HYPOTHESIS: We hypothesized that patellofemoral cartilage thickness would decrease immediately after exercise and return to its baseline thickness by the following morning in asymptomatic male runners. We further hypothesized that we would observe a significant distance-related dose response, with larger compressive strains (defined here as the mean change in cartilage thickness measured immediately after exercise, divided by the pre-exercise cartilage thickness) observed immediately after 10-mile runs compared with 3-mile runs. STUDY
designDescriptive laboratory study.
methodsEight asymptomatic male participants underwent magnetic resonance imaging of their dominant knee before, immediately after, and 24 hours after running 3 and 10 miles at a self-selected pace (on separate visits).
resultsMean patellar cartilage thicknesses measured before exercise and after the 24-hour recovery period were significantly greater than the thicknesses measured immediately after both the 3- and 10-mile runs (
conclusionPatellar cartilage thickness decreased immediately after running and returned to its baseline thickness within 24 hours of running up to 10 miles. Furthermore, patellar cartilage compressive strains were dose-dependent immediately after exercise. CLINICAL RELEVANCE: These findings provide critical baseline data for understanding patellofemoral cartilage biomechanics in asymptomatic male runners that may be used to optimize exercise protocols and investigations targeting those with running-induced patellofemoral pain.
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