ArticleJournal of immunology research2020
Anemoside B4 Protects against Acute Lung Injury by Attenuating Inflammation through Blocking NLRP3 Inflammasome Activation and TLR4 Dimerization.
Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- Anemoside B4 upregulates DDAH2 and attenuates oxidative stress induced endothelial dysfunction.Molecular and cellular biochemistry · 2026Article
- The Combination of Chinese Medicine Monomers Reduces 7S Globulin-Induced Damage to IPEC-J2 Cells In Vitro by Modulating NF-κB/MAPK Pathway-Related Markers.Veterinary sciences · 2026Article
- Anti-Complement, Anti-Oxidative, and Anti-Inflammatory Activities of the Ethanol Extract ofPlants (Basel, Switzerland) · 2026Article
- Anemoside B4 inhibits mitochondrial dysfunction-related mitophagy in asthma by regulating KAT2B/IRF3 axis.Molecular and cellular biochemistry · 2026Article
- Pulsatilla Saponin B4 Ameliorates LPS-Induced Inflammatory Response by Inhibiting IL-17RA and MAPK/NF-κB Signaling in Bovine Mammary Epithelial Cells and Mastitis Mouse Model.Veterinary sciences · 2026Article
- [Anemoside B4 inhibits non-small cell lung cancer metastasis by modulating epithelial-mesenchymal transition mediated by the MAPK and Keap1/Nrf2 signaling pathways].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026Article
- A "controlled assembly" strategy for constructingBioactive materials · 2026Article
- An Analysis of Effective Components of Pulsatillae radix Using UHPLC-QTOF- MS/MS and Network Pharmacology to Investigate its Effects on Ulcerative Colitis.Combinatorial chemistry & high throughput screening · 2026Article
- NLRP3 inflammasome in acute lung injury: Cumulative evidence for traditional Chinese medicine and natural products.Chinese herbal medicines · 2025Review
- Pulsatilla saponin inhibits the proliferation of keratinocytes and ameliorates imiquimod-induced psoriasis through the NF-κB and STAT3 signaling pathways.Journal of traditional and complementary medicine · 2025Article
- Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.Frontiers in pharmacology · 2025Article
- Efficacy of Pulsatilla saponin B4 for treatment dairy cows affected with clinical mastitis.PloS one · 2025Article
- Effect of anemoside B4 on ameliorating cerebral ischemic/reperfusion injury.Iranian journal of basic medical sciences · 2025Article
- Efficacy and safety of anemoside B4 in canine pneumonia treatment: a prospective, randomized controlled trial.Frontiers in veterinary science · 2025Article
- Anemoside B4 mitigates endoplasmic reticulum stress-induced apoptosis post cerebral ischemia/reperfusion injury in rats.Iranian journal of basic medical sciences · 2025Article
- Article
- Anemoside B4, a new pyruvate carboxylase inhibitor, alleviates colitis by reprogramming macrophage function.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- Anemoside B4 alleviates arthritis pain via suppressing ferroptosis-mediated inflammation.Journal of cellular and molecular medicine · 2024Article
- Anemoside B4 attenuates abdominal aortic aneurysm by limiting smooth muscle cell transdifferentiation and its mediated inflammation.Frontiers in immunology · 2024Article
- Anemoside B4 inhibits SARS-CoV-2 replicationChinese herbal medicines · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Acute lung injury (ALI) is an acute inflammatory process in the lung parenchyma. Anemoside B4 (B4) was isolated from Pulsatilla, a plant-based drug against inflammation and commonly applied in traditional Chinese medicine. However, the anti-inflammatory effect and the mechanisms of B4 are not clear. In this study, we explored the potential mechanisms and anti-inflammatory activity of B4 both
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.