Evidence map›Paper›PMID 33344513›Full record

ArticleFrontiers in cardiovascular medicine2020

Pandemic Perspective: Commonalities Between COVID-19 and Cardio-Oncology.

Sherry-Ann Brown, Svetlana Zaharova, Peter Mason, Jonathan Thompson, Bicky Thapa, David Ishizawar, Erin Wilkes, Gulrayz Ahmed, Jason Rubenstein, Joyce Sanchez and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Cardio-oncology and COVID 19: Lessons learned, past reflections and future deliberations.American heart journal plus : cardiology research and practice · 2022
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Sherry-Ann BrownCardio-Oncology Program, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Svetlana ZaharovaCardio-Oncology Program, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Peter MasonDivision of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Jonathan ThompsonDivision of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Bicky ThapaDivision of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
David IshizawarDivision of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Erin WilkesDepartment of Pharmacy, Froedtert Health and Medical College of Wisconsin, Milwaukee, WI, United States.
Gulrayz AhmedDivision of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, United States.
Jason RubensteinDivision of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Joyce SanchezDivision of Infectious Diseases, Medical College of Wisconsin, Milwaukee, WI, United States.
David JoyceDivision of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.
Balaraman KalyanaramanDepartment of Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States.
Michael WidlanskyDivision of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.
Medical College of Wisconsin · USFroedtert Hospital · US

Funding

Impact of L. plantarum 299v Supplementation on Endothelial Function and Systemic InflammationR01HL144098 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2019 to 2022
$2.9M
Endothelial function in human diabetes: role of mitochondrial fission proteinsR01HL128240 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2016 to 2020
$2.9M
Impact of L. plantarum 299v supplementation on endothelial function and inflammation in humans with type 2 diabetesK24HL152143 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI WIDLANSKY, MICHAEL E · 2021 to 2025
$572k
NHLBI NIH HHS K24 HL152143NHLBI NIH HHS R01 HL128240NHLBI NIH HHS R01 HL144098
6 · The paper itself

Abstract

Overlapping commonalities between coronavirus disease of 2019 (COVID-19) and cardio-oncology regarding cardiovascular toxicities (CVT), pathophysiology, and pharmacology are special topics emerging during the pandemic. In this perspective, we consider an array of CVT common to both COVID-19 and cardio-oncology, including cardiomyopathy, ischemia, conduction abnormalities, myopericarditis, and right ventricular (RV) failure. We also emphasize the higher risk of severe COVID-19 illness in patients with cardiovascular disease (CVD) or its risk factors or cancer. We explore commonalities in the underlying pathophysiology observed in COVID-19 and cardio-oncology, including inflammation, cytokine release, the renin-angiotensin-aldosterone-system, coagulopathy, microthrombosis, and endothelial dysfunction. In addition, we examine common pharmacologic management strategies that have been elucidated for CVT from COVID-19 and various cancer therapies. The use of corticosteroids, as well as antibodies and inhibitors of various molecules mediating inflammation and cytokine release syndrome, are discussed. The impact of angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) is also addressed, since these drugs are used in cardio-oncology and have received considerable attention during the COVID-19 pandemic, since the culprit virus enters human cells

Indexed as

cardio-oncologyCOVID-19cytokine release syndromehealth disparitiesinflammationpandemicright ventricletelemedicine

Identifiers

PMID33344513
PMCPMC7746643
OpenAlexW3112472866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.