Evidence map›Paper›PMID 33344268›Full record

ReviewFrontiers in cellular and infection microbiology2020

A Comparison of Stage Conversion in the Coccidian Apicomplexans

Sarah L Sokol-Borrelli, Rachel S Coombs, Jon P Boyle

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Microorganisms · 2026
    Review
  3. Article
  4. Toxoplasma gondii and the Brain: Frenemies? Or Just Outright Foes?Journal of the Pediatric Infectious Diseases Society · 2025
    Review
  5. Article
  6. Article
  7. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Evaluation of species-specific polyclonal antibodies to detect and differentiate betweenJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  11. Article
  12. Review
  13. Advances towards the completeFaculty reviews · 2023
    Review
  14. Article
  15. Mining the Proteome ofAnimals : an open access journal from MDPI · 2022
    Review
  16. Article
  17. Article
  18. Seroprevalence ofFrontiers in veterinary science · 2022
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarah L Sokol-BorrelliUniversity of Pittsburgh, Department of Biological Sciences, Kenneth P. Dietrich School of Arts and Sciences, Pittsburgh, PA, United States.
Rachel S CoombsUniversity of Pittsburgh, Department of Biological Sciences, Kenneth P. Dietrich School of Arts and Sciences, Pittsburgh, PA, United States.
Jon P BoyleUniversity of Pittsburgh, Department of Biological Sciences, Kenneth P. Dietrich School of Arts and Sciences, Pittsburgh, PA, United States.

Funding

Comparative and functional genomics of Toxoplasma and Hammondia hammondiR01AI116855 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOYLE, JON P · 2015 to 2024
$3.2M
Elucidating the mechanisms driving stage conversion in Toxoplasma gondii and Hammondia hammondiF31AI140529 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SOKOL, SARAH LOUISE · 2019 to 2021
$51k
NIAID NIH HHS F31 AI140529NIAID NIH HHS R01 AI116855
6 · The paper itself

Abstract

Stage conversion is a critical life cycle feature for several Apicomplexan parasites as the ability to switch between life forms is critical for replication, dissemination, pathogenesis and ultimately, transmission to a new host. In order for these developmental transitions to occur, the parasite must first sense changes in their environment, such as the presence of stressors or other environmental signals, and then respond to these signals by initiating global alterations in gene expression. As our understanding of the genetic components required for stage conversion continues to broaden, we can better understand the conserved mechanisms for this process and unique components and their contribution to pathogenesis by comparing stage conversion in multiple closely related species. In this review, we will discuss what is currently known about the mechanisms driving stage conversion in

Indexed as

CoccidiosisNeosporaSarcocystidaeToxoplasmaHumansSpecies SpecificitybradyzoiteHammondia hammondiNeospora caninumtissue cystsToxoplasma gondii

Identifiers

PMID33344268
PMCPMC7744739

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.