Evidence map›Paper›PMID 33344238›Full record

ReviewFrontiers in oncology2020

DNA Copy Number Changes in Diffuse Large B Cell Lymphomas.

Luciano Cascione, Luca Aresu, Michael Baudis, Francesco Bertoni

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  9. Barriers to achieving a cure in lymphoma.Cancer drug resistance (Alhambra, Calif.) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Luciano CascioneInstitute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.
Luca AresuDepartment of Veterinary Science, University of Turin, Grugliasco, Italy.
Michael BaudisSIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Francesco BertoniInstitute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.
SIB Swiss Institute of Bioinformatics · CHInstitute of Oncology Research · CHUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copy number aberrations (CNV/CNA) represent a major contribution to the somatic mutation landscapes in cancers, and their identification can lead to the discovery of oncogenetic targets as well as improved disease (sub-) classification. Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma in Western Countries and up to 40% of the affected individuals still succumb to the disease. DLBCL is an heterogenous group of disorders, and we call DLBCL today is not necessarily the same disease of a few years ago. This review focuses on types and frequencies of regional DNA CNVs in DLBCL, not otherwise specified, and in two particular conditions, the transformation from indolent lymphomas and the DLBCL in individuals with immunodeficiency.

Indexed as

CDKN2Acopy number aberrationsdiffuse large B cell lymphomagenetic alterationhematological malignancieslymphomaMYCTP53

Identifiers

PMID33344238
PMCPMC7740002
OpenAlexW3107180188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.