Evidence map›Paper›PMID 33344124›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Controllable Assembly of Upconversion Nanoparticles Enhanced Tumor Cell Penetration and Killing Efficiency.

Zhen Zhang, Juwita Norasmara Rahmat, Ratha Mahendran, Yong Zhang

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhen ZhangDepartment of Biomedical Engineering Faculty of Engineering National University of Singapore Singapore 117583 Singapore.ORCID https://orcid.org/0000-0001-5760-7055
Juwita Norasmara RahmatDepartment of Biomedical Engineering Faculty of Engineering National University of Singapore Singapore 117583 Singapore.
Ratha MahendranDepartment of Surgery Yong Loo Lin School of Medicine National University of Singapore Singapore 119228 Singapore.
Yong ZhangDepartment of Biomedical Engineering Faculty of Engineering National University of Singapore Singapore 117583 Singapore.ORCID https://orcid.org/0000-0002-1303-0458
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of upconversion nanoparticles (UCNPs) for treating deep-seated cancers and large tumors has recently been gaining momentum. Conventional approaches for loading photosensitizers (PS) to UCNPs using noncovalent physical adsorption and covalent conjugation had been previously described. However, these methods are time-consuming and require extra modification steps. Incorporating PS loading during the controlled UCNPs assembly process is seldom reported. In this study, an amphiphilic copolymer, poly(styrene-

Indexed as

clustersnanoparticle assemblyphotodynamic therapytumor cell penetrationupconversion

Identifiers

PMID33344124
PMCPMC7739948
OpenAlexW3098363853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.