Evidence map›Paper›PMID 33344110›Full record

ArticleCurrent geriatrics reports2020

Effect of prehabilitation in older adults undergoing total joint replacement: An Overview of Systematic Reviews.

Gustavo J Almeida, Samannaaz S Khoja, Boris A Zelle

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Current geriatrics reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07356466 (Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma), which is not on this map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07356466 early_phase1enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: A Single-Center Randomized Controlled Trial

TypeinterventionalSponsorFujian Medical UniversityRan2025 to 2030Enrolled100ConditionsGastric (Stomach) CancerArmsPucotenlimab Combined with Lenvatinib, Oxaliplatin plus S-1 regimen
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gustavo J AlmeidaDepartment of Physical Therapy, School of Health Professions, University of Texas Health Science Center at San Antonio; Department of Orthopaedics, Long School of Medicine, University of Texas Health Science Center at San Antonio.
Samannaaz S KhojaDepartment of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh.
Boris A ZelleDepartment of Orthopaedics, Long School of Medicine, University of Texas Health Science Center at San Antonio.
The University of Texas Health Science Center at San Antonio · USUniversity of Pittsburgh · US

Funding

San Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Adam Salmon · 2015 to 2026
$14.1M
NIA NIH HHS P30 AG044271
6 · The paper itself

Abstract

purpose of reviewTo review and discuss the findings of systematic reviews that synthesized the evidence on the effect of preoperative exercises (prehabilitation) on postoperative functional recovery in older adults undergoing total knee or hip joint replacement. RECENT

findingsTen systematic reviews (8 meta-analyses) were included in this review. Findings from the systematic reviews indicated that prehabilitation decreases length of hospital stay but does not improve postoperative functional recovery in older adults undergoing joint replacement. Individual studies in the systematic reviews varied considerably in prehabilitation protocol, assessment timepoints, and outcome measures. Most importantly, systematic reviews did not assess the outcomes pre-post prehabilitation as this timepoint was not addressed in most individual studies. Therefore, it is not known whether the prehabilitation programs improved outcomes preoperatively. SUMMARY: There is a need to develop comprehensive prehabilitation protocols and systematically assess the preoperative and postoperative effectiveness of prehabilitation protocols on functional outcomes (i.e., self-reported and performance-based) in older adults undergoing total joint replacement.

Indexed as

osteoarthritisphysical functionprehabilitationpreoperative exercisetotal hip replacementtotal knee replacement

Identifiers

PMID33344110
PMCPMC7745772
OpenAlexW3107565766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.