Evidence map›Paper›PMID 33344067›Full record

ArticleCurrent pathobiology reports2019

Advances in Diffusion and Perfusion MRI for Quantitative Cancer Imaging.

Mehran Baboli, Jin Zhang, Sungheon Gene Kim

Abstract read
In one paragraph

Article in Current pathobiology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mehran BaboliCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY 10016, USA.
Jin ZhangCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY 10016, USA.
Sungheon Gene KimCenter for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY 10016, USA.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
DCE MRI Study for Breast Cancer.R01CA160620 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, SUNGHEON GENE · 2012 to 2023
$5.4M
Gradient-Echo Spectroscopic Imaging Study of Saturated Fat and Breast CancerR01CA219964 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, SUNGHEON GENE, MOY, LINDA · 2018 to 2022
$2.3M
Diffusion MRI of Treatment Response for De-escalation of Radiation TherapyUH3CA228699 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, SUNGHEON GENE · 2021 to 2023
$1.2M
Diffusion MRI of Treatment Response for De-escalation of Radiation TherapyUG3CA228699 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, SUNGHEON GENE · 2019 to 2020
$807k
NCI NIH HHS R01 CA160620NCI NIH HHS R01 CA219964NCI NIH HHS UG3 CA228699NCI NIH HHS UH3 CA228699NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

purpose of reviewThis article is to review recent technical developments and their clinical applications in cancer imaging quantitative measurement of cellular and vascular properties of the tumors. RECENT

findingsRapid development of fast Magnetic Resonance Imaging (MRI) technologies over last decade brought new opportunities in quantitative MRI methods to measure both cellular and vascular properties of tumors simultaneously. SUMMARY: Diffusion MRI (dMRI) and dynamic contrast enhanced (DCE)-MRI have become widely used to assess the tissue structural and vascular properties, respectively. However, the ultimate potential of these advanced imaging modalities has not been fully exploited. The dependency of dMRI on the diffusion weighting gradient strength and diffusion time can be utilized to measure tumor perfusion, cellular structure, and cellular membrane permeability. Similarly, DCE-MRI can be used to measure vascular and cellular membrane permeability along with cellular compartment volume fractions. To facilitate the understanding of these potentially important methods for quantitative cancer imaging, we discuss the basic concepts and recent developments, as well as future directions for further development.

Indexed as

Cancer imagingDCE-MRIDiffusion MRIMicrostructurePerfusionWater Exchange

Identifiers

PMID33344067
PMCPMC7747414

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.