ArticleJournal of ophthalmology2020
Association between Corneal Stiffness Parameter at the First Applanation and Keratoconus Severity.
Article in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- A Comparative and Prospective Study of Corneal Consumption and Corneal Biomechanics After SMILE and FS-LASIK Performed on the Contralateral Eyes With High Myopic Astigmatism.Translational vision science & technology · 2024Trial
- Staging of Keratoconus Indices Based on Localized Corneal Biomechanics Stress-Strain Index Map.Ophthalmology science · 2026Article
- Corneal Biomechanics Before and After Descemet Membrane Endothelial Keratoplasty in Patients with Fuchs Endothelial Corneal Dystrophy.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Visual, Tomographic, and Biomechanical Outcomes of CAIRS with Accelerated Cross-Linking in Moderate to Advanced Keratoconus: A 6-Month Retrospective Case Series.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Mediating roles of corneal biomechanical and topographic parameters in eye rubbing and keratoconus based on the Chinese keratoconus cohort study.Frontiers in bioengineering and biotechnology · 2025Article
- The Chinese keratoconus (CKC) cohort study.European journal of epidemiology · 2024Article
- New dawn for keratoconus treatment: potential strategies for corneal stromal regeneration.Stem cell research & therapy · 2023Review
- Effects of femtosecond laser-assisted minimally invasive lamellar keratoplasty (FL-MILK) on mild-to-moderate and advanced keratoconus.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Machine learning analysis with the comprehensive index of corneal tomographic and biomechanical parameters in detecting pediatric subclinical keratoconus.Frontiers in bioengineering and biotechnology · 2023Article
- Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis.Cell discovery · 2022Article
- The Limbal Niche and Regenerative Strategies.Vision (Basel, Switzerland) · 2021Review
- A hospital-based study on clinical data, demographic data and visual function of keratoconus patients in Central China.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study aimed to evaluate the character of corneal stiffness parameter at the first applanation (SP-A1) in normal and keratoconus eyes and explore the association between SP-A1 and keratoconus severity indicators.
methodsA total of 351 normal and 351 keratoconus eyes were included in the current study. Keratoconus was diagnosed according to the corneal topography map and slit-lamp examination. The severity of keratoconus was classified to mild (steep keratometry (Ks) < 48D), moderate (48 ≤ Ks < 55D), and severe (Ks ≥ 55D). The SP-A1 was measured using the Corvis ST software. The correlation analyses and receiver operating characteristic (ROC) curve were performed in the current analysis.
resultsThe SP-A1 values of keratoconus were lower than that of normal eyes (72.11 (57.02, 83.08) mmHg/mm vs 110.89 (100.45, 122.47) mmHg/mm,
conclusionsThe SP-A1 value decreased while the keratoconus severity increased. It was lower in keratoconus than that in normal eyes and could be helpful in identifying keratoconus eyes from normal eyes. Further researches would be warranted to expand the clinical utility of SP-A1.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.