Evidence map›Paper›PMID 33343700›Full record

ArticleEcancermedicalscience2020

Health resource utilisation by patients with neuroendocrine tumours with or without carcinoid heart disease: a multinational study.

Hugo Tanaka, Deise Uema, Juliana F M Rego, Rui F Weschenfelder, Nathalia D'Agustini, Duilio R Rocha Filho, Juan M O'Connor, Romina Luca, Jose Eduardo R Nuñez, Milton José de Barros E Silva and 1 more

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In one paragraph

Article in Ecancermedicalscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hugo TanakaDepartment of Clinical Oncology, AC Camargo Cancer Center, São Paulo 01509-900, Brazil.
Deise UemaDivision of Health Care Sciences Center for Clinical Research and Management Education Dresden.
Juliana F M RegoHospital Universitário Onofre Lopes, Natal 59012-300, Brazil.
Rui F WeschenfelderHospital Moinhos de Vento, Porto Alegre 90035-001, Brazil.
Nathalia D'AgustiniHospital Moinhos de Vento, Porto Alegre 90035-001, Brazil.
Duilio R Rocha FilhoHospital Universitário Walter Cantídio, Fortaleza 60420-570, Brazil.
Juan M O'ConnorHospital de Gastroenterología Bonorino Udaondo, C1264AAA Buenos Aires, Argentina.
Romina LucaHospital de Gastroenterología Bonorino Udaondo, C1264AAA Buenos Aires, Argentina.
Jose Eduardo R NuñezInstituto do Câncer do Estado de São Paulo, São Paulo, Brazil.
Milton José de Barros E SilvaDepartment of Clinical Oncology, AC Camargo Cancer Center, São Paulo 01509-900, Brazil.
Rachel P RiechelmannDepartment of Clinical Oncology, AC Camargo Cancer Center, São Paulo 01509-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarcinoid heart disease (CHD) is a rare and severe complication from carcinoid syndrome which may be associated with high health resource utilisation (HRU). We aimed to compare HRU between patients with and without CHD.

methodsMulticentre retrospective study of 137 consecutive patients with neuroendocrine tumours (NET) and elevated urinary 5-hydroxyindoleacetic acid treated in seven large hospitals in Latin America. We used the chi-squared test for binary variables and the Mann-Whitney test for quantitative correlations. Variables were entered into a multivariable linear regression model for higher HRU.

resultsOne-third of the patients had (45) had CHD. Patients with CHD had significantly more emergency visits and echocardiograms as compared to patients without CHD. In the bivariate models, CHD (R

conclusionsNET patients with CHD present higher HRU independently of other clinical factors or health system. Effectively treating carcinoid syndrome, and likely delaying the onset of CHD, may potentially reduce the amount of HRU by these patients.

Indexed as

carcinoid hearthealth resourceLatin Americaneuroendocrine tumourspublic health

Identifiers

PMID33343700
PMCPMC7738266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.