ArticleFrontiers in genetics2020
Validation of Susceptibility Loci for Vitiligo Identified by GWAS in the Chinese Han Population.
Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Genetics of Vitiligo: A Review.Clinical, cosmetic and investigational dermatology · 2026Review
- The role of JAK3 and TEC family kinases in vitiligo pathogenesis.Frontiers in immunology · 2026Review
- NLRP1 gene polymorphism rs2670660 is associated with vitiligo in the Pakistani population.Molecular biology reports · 2025Article
- Beyond skin deep: exploring the complex molecular mechanisms and holistic management strategies of vitiligo.Archives of dermatological research · 2025Review
- Association of herpes simplex virus infection and vitiligo: a nationwide retrospective cohort study.Archives of dermatological research · 2024Article
- Exploring the Genetic Landscape of Vitiligo in the Pura Raza Español Horse: A Genomic Perspective.Animals : an open access journal from MDPI · 2024Article
- Estimation of genetic variation in vitiligo associated genes: Population genomics perspective.BMC genomic data · 2024Article
- Exploring the immunological landscape of osteomyelitis through mendelian randomization analysis.Frontiers in genetics · 2024Article
- [Association of gene polymorphisms ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Association AmongClinical, cosmetic and investigational dermatology · 2022Article
- Deleterious effect of angiotensin-converting enzyme gene polymorphism in vitiligo patients.Saudi journal of biological sciences · 2021Article
- Variations inInternational journal of general medicine · 2021Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Forty-nine susceptible loci have been reported to be significantly associated with vitiligo by genome-wide association studies (GWASs) in European-derived whites. To date, some of these reported susceptibility loci have not yet been validated in the Chinese Han population. The purpose of this study was to examine whether the 16 reported susceptible loci in European-derived whites were associated with vitiligo in the Chinese Han population. Imputation was performed using our previous GWAS dataset by IMPUTE v2.2.2. The 16 imputed top single-nucleotide polymorphisms (SNPs) with suggestive signals, together with the reported SNPs, were genotyped in a total of 2581 patients and 2579 controls by the Sequenom MassARRAY system. PLINK 2.0 software was used to perform association analysis. The dbSNP database, HaploReg, and eQTL data were adopted to annotate the biological function of the SNPs. Finally, four SNPs from three loci were significantly associated with vitiligo, including rs3747517 (
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