ReviewFrontiers in immunology2020
Skin Immunity to Dermatophytes: From Experimental Infection Models to Human Disease.
Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 74 citations in OpenAlex.
- Non-coding RNAs in dermatophytosis: Key regulators of host-fungal interactions and pathogenesis-A review.Virulence · 2026Review
- Dermatophytosis: An Update on Global Epidemiology.Journal of fungi (Basel, Switzerland) · 2026Review
- Eruptive inflammatory tinea corporis: a case report highlighting the role of molecular testing on formalin-fixed tissue in confirming the causative species.AME case reports · 2026Article
- Development and In Vivo Evaluation of QbD-Assisted Squalene-based Luliconazole Entrapped Ethosomal Gel for the Skin Fungal Infection.AAPS PharmSciTech · 2025Article
- Comparative gene expression analysis in closely related dermatophytes reveals secondary metabolism as a candidate driver of virulence.Microbiology spectrum · 2025Article
- Article
- Cutaneous Innate Lymphoid Populations Drive IL-17A-Mediated Immunity in Nannizzia gypsea Dermatophytosis.The Journal of investigative dermatology · 2025Article
- Unmasking Tinea Incognito: Case Study, Insights Into the Pathogenesis, and Recommendations.Cureus · 2024Article
- Study on the chemical composition and anti-fungi activities of anthraquinones and its glycosides from Rumex japonicus Houtt.Journal of natural medicines · 2024Article
- An efficient gene targeting system using Δku80 and functional analysis of Cyp51A in Trichophyton rubrum.AMB Express · 2024Article
- Host-Pathogen Interaction and Resistance Mechanisms in Dermatophytes.Pathogens (Basel, Switzerland) · 2024Review
- The Preparation and Evaluation of a Hydrochloride Hydrogel Patch with an Iontophoresis-Assisted Release of Terbinafine for Transdermal Delivery.Gels (Basel, Switzerland) · 2024Article
- Comparative Transcriptome Analysis of T. rubrum, T. mentagrophytes, and M. gypseum Dermatophyte Biofilms in Response to Photodynamic Therapy.Mycopathologia · 2024Article
- Fungal coexistence in the skin mycobiome: a study involving Malassezia, Candida, and Rhodotorula.AMB Express · 2024Article
- Molecular Signaling and Metabolic Responses during the Interaction between Human Keratinocytes (HaCaT) and the DermatophyteJournal of fungi (Basel, Switzerland) · 2024Article
- [Trichophyton mentagrophytes genotype VII increasingly causes anogenital infections].Dermatologie (Heidelberg, Germany) · 2024Review
- Erythroderma combined with deeper dermal dermatophytosis due to Trichophyton rubrum in a patient with myasthenia gravis: first case report and literature review.BMC infectious diseases · 2023Review
- Transcriptome Analysis of Co-Cultures of THP-1 Human Macrophages with Inactivated GerminatedJournal of fungi (Basel, Switzerland) · 2023Article
- Molecular study of feline dermatophytosis and Toll-like receptor 2 and 4 gene expression in their lesions.Veterinary medicine and science · 2023Article
- New insights into immunity to skin fungi shape our understanding of health and disease.Parasite immunology · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dermatophytoses (ringworms) are among the most frequent skin infections and are a highly prevalent cause of human disease worldwide. Despite the incidence of these superficial mycoses in healthy people and the compelling evidence on chronic and deep infections in immunocompromised individuals, the mechanisms controlling dermatophyte invasion in the skin are scarcely known. In the last years, the association between certain primary immunodeficiencies and the susceptibility to severe dermatophytosis as well as the evidence provided by novel experimental models mimicking human disease have significantly contributed to deciphering the basic immunological mechanisms against dermatophytes. In this review, we outline the current knowledge on fungal virulence factors involved in the pathogenesis of dermatophytoses and recent evidence from human infections and experimental models that shed light on the cells and molecules involved in the antifungal cutaneous immune response. The latest highlights emphasize the contribution of C-type lectin receptors signaling and the cellular immune response mediated by IL-17 and IFN-γ in the anti-dermatophytic defense and skin inflammation control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.