ArticleFrontiers in psychiatry2020
Neurocognition and Social Cognition Predicting 1-Year Outcomes in First-Episode Psychosis.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Disentangling the Relationships Between the Clinical Symptoms of Schizophrenia Spectrum Disorders and Theory of Mind: A Meta-analysis.Schizophrenia bulletin · 2023Pooled it
- A network approach exploring the effects of cognitive remediation on cognition, symptoms, and functioning in early psychosis.Psychological medicine · 2025Trial
- A combined exercise and cognitive training intervention induces fronto-cingulate cortical plasticity in first-episode psychosis patients.Schizophrenia research · 2023Trial
- Efficacy of metacognitive therapies in first-episode psychosis: a systematic review.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026Article
- Negative association between cognitive functioning and antipsychotic DPsychological medicine · 2026Article
- Neuroinflammation and white matter microstructure as mediators of cognitive deficits in offspring of parents with bipolar disorder.Brain communications · 2026Article
- Neuropsychological profiles in first-episodes psychosis and their relationship with clinical, metacognition and social cognition variables.European archives of psychiatry and clinical neuroscience · 2025Article
- The relationship between cognitive and global function in patients with schizophrenia and mood disorders: a transdiagnostic network analysis.Frontiers in psychiatry · 2025Article
- Biomarker discovery using machine learning in the psychosis spectrum.Biomarkers in neuropsychiatry · 2024Article
- Personalized Cognitive Health in Psychiatry: Current State and the Promise of Computational Methods.Schizophrenia bulletin · 2024Review
- Functional phenotypes in schizophrenia spectrum disorders: defining the constructs and identifying biopsychosocial correlates using data-driven methods.Schizophrenia (Heidelberg, Germany) · 2024Article
- Cognitive Inflexibility Predicts Negative Symptoms Severity in Patients with First-Episode Psychosis: A 1-Year Follow-Up Study.Brain sciences · 2024Article
- Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium.Molecular psychiatry · 2023Article
- Extrapyramidal symptoms predict cognitive performance after first-episode psychosis.Schizophrenia (Heidelberg, Germany) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive performance at illness onset may predict outcomes in first-episode psychosis (FEP), and the change in cognition may associate with clinical changes. Cognitive testing was administered to 54 FEP participants 2 months after entering treatment and to 39 participants after 1 year. We investigated whether baseline cognition predicted 1-year outcomes beyond positive, negative, and affective symptoms and whether the trajectory of cognition associated with clinical change. Baseline overall neurocognitive performance predicted the 1-year social and occupational level, occupational status, and maintaining of life goals. The domain of processing speed associated with the 1-year remission, occupational status, and maintaining of life goals. Baseline social cognition associated with occupational status a year later and the need for hospital treatment during the 1st year after FEP. Most of the associations were retained beyond baseline positive and affective symptom levels, but when accounting for negative symptoms, cognition no longer predicted 1-year outcomes, highlighting how negative symptoms overlap with cognition. The trajectory of neurocognitive performance over the year did not associate with changes in symptoms or functioning. Cognitive testing at the beginning of treatment provided information on the 1-year outcome in FEP beyond positive and affective symptom levels. In particular, the domains of processing speed and social cognition could be targets for interventions that aim to improve the outcome after FEP.
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