Evidence map›Paper›PMID 33343427›Full record

ArticleFrontiers in psychiatry2020

Aggressive and Disruptive Behavior Among Psychiatric Patients With Major Depressive Disorder, Schizophrenia, or Alcohol Dependency and the Effect of Depression and Self-Esteem on Aggression.

Michael Fritz, Riad Shenar, Lizbeth Cardenas-Morales, Markus Jäger, Judith Streb, Manuela Dudeck, Irina Franke

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07434479 (A Virtual Reality Mindfulness Application for Aggression in Schizophrenia), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07434479 narecruitingnot on this mapstarted 2026, after this paper: background citation

A Virtual Reality Mindfulness Application for Aggression in Schizophrenia

TypeinterventionalSponsorManhattan Psychiatric CenterRan2026 to 2027Enrolled58ConditionsSchizophrenia Disorder, Schizoaffecitve Disorder, AggressionArmsMindfulness-Based Virtual Reality Intervention
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Extract ofFrontiers in pharmacology · 2022
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael FritzDepartment of Forensic Psychiatry and Psychotherapy, Ulm University, Ulm, Germany.
Riad ShenarDepartment of Forensic Psychiatry and Psychotherapy, Ulm University, Ulm, Germany.
Lizbeth Cardenas-MoralesDepartment of Forensic Psychiatry and Psychotherapy, Ulm University, Ulm, Germany.
Markus JägerDepartment of Psychiatry, Psychotherapy and Psychosomatics, District Hospital Kempten, Kempten, Germany.
Judith StrebDepartment of Forensic Psychiatry and Psychotherapy, Ulm University, Ulm, Germany.
Manuela DudeckDepartment of Forensic Psychiatry and Psychotherapy, Ulm University, Ulm, Germany.
Irina FrankeDepartment of Forensic Psychiatry, Psychiatric Services Graubuenden, Cazis, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggressive and disruptive behavior in inpatient settings poses a serious challenge for clinical staff and fellow patients. Hence, the aim of this study was to identify different aspects of aggressive and disruptive behavior in the context of an aberrant self-esteem or clinically manifested depression as potentially influencing factors. We collected self-reported data from 282 psychiatric patients [ICD-10 diagnoses for alcohol dependency, schizophrenia or major depressive disorder (MDD)] and compared it to healthy norm groups. As expected, all three patient groups scored higher in the aggression questionnaires than the norm group. Specifically, patients with MDD exhibited significantly higher externally directed aggression, reactive aggression, and irritability compared to controls. Patients with schizophrenia displayed higher irritability, while all three groups showed distinctly higher self-aggressiveness than healthy persons. We found a lower inhibition of aggression in alcohol dependent subjects compared to both the patient groups and the norm sample. Yet, the higher the self-esteem among alcohol dependent and MDD patients, the lower were their aggression scores; similarly, a lower self-esteem among patients diagnosed with schizophrenia resulted in heighten self-aggressiveness. Thus, our data suggests that therapeutic interventions for strengthening self-esteem in patients with a diagnosis of MDD, alcohol dependency or schizophrenia could reduce certain aspects of aggressive behavior. Therefore, it seems conceivable that strengthening self-esteem in psychiatric patients could contribute to the prevention of violence in clinical practice.

Indexed as

addictionaggressioncrime and mental healthdepressionschizophrenia

Identifiers

PMID33343427
PMCPMC7744284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.