ArticleFrontiers in psychiatry2020
Impacts of Stressful Life Events and Traumatic Experiences on Onset of Obsessive-Compulsive Disorder.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of Post-mortem Brain Tissue in Investigations of Obsessive- Compulsive Disorder: A Systematic Review.Current neuropharmacology · 2024Pooled it
- Cariprazine-induced obsessive-compulsive symptoms in a patient with bipolar II disorder: A case report.Biomedical reports · 2026Article
- "It Doesn't Matter Where OCD Comes From," or Does It?Current psychiatry reports · 2026Review
- Increased Serum GLO-1 Levels Are Associated With the Pathophysiology and Development of Obsessive-Compulsive Disorder: Findings From a Case-Control Study.Health science reports · 2026Article
- Trauma-Related Compulsions in Obsessive-Compulsive Disorder: Functional Insights From Factor Analysis.Stress and health : journal of the International Society for the Investigation of Stress · 2026Article
- Acute Trauma and Obsessive Compulsive Disorder: Evidence from October 7th, 2023.Psychotherapy and psychosomatics · 2026Article
- Psychometric Evaluation of the Over-Cleanliness Scale (OCS) Amid Covid-19 Pandemic and the Role of Perceived Stress and OCD Proneness on Over-Cleanliness: A Cross-Sectional Study.Health science reports · 2025Article
- Obsessive-compulsive symptoms as a unique presentation of complex posttraumatic stress disorder in Southeast Asia: a case report.Journal of medical case reports · 2025Article
- Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury.Inflammopharmacology · 2025Article
- Impact of traumatic experiences on obsessive-compulsive disorder: a study of Palestinians in the Gaza Strip - a conflict area.European journal of psychotraumatology · 2024Article
- Obsessive-Compulsive Symptoms in the General Population Under Stressful Conditions: Lessons Learned from the COVID-19 Pandemic.Brain sciences · 2024Article
- Obsessive-Compulsive Disorder with a Religious Focus: An Observational Study.Journal of clinical medicine · 2024Article
- Regional brain activity and connectivity associated with childhood trauma in drug-naive patients with obsessive-compulsive disorder.Scientific reports · 2024Article
- Exploring the Interplay between Complex Post-Traumatic Stress Disorder and Obsessive-Compulsive Disorder Severity: Implications for Clinical Practice.Medicina (Kaunas, Lithuania) · 2024Article
- Association of granulocyte macrophage colony-stimulating factor and interleukin-17 levels with obsessive-compulsive disorder: a case-control study findings.Scientific reports · 2023Article
- Socioeconomic resources moderate the relationship between maternal prenatal obsessive-compulsive symptoms and infant negative affectivity.Infant behavior & development · 2023Article
- Psychotherapies and digital interventions for OCD in adults: What do we know, what do we need still to explore?Comprehensive psychiatry · 2023Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Not a few patients with obsessive-compulsive disorder (OCD) have experienced events that affected the onset. The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD. It would be useful to understand the experiences surrounding the onset, including stressful life events and traumatic experiences, for comprehension of the pathophysiology of OCD. In the present study, we investigated the onset conditions of 281 patients with OCD and compared clinical characteristics among groups with or without stressful life events including traumatic experiences. As a result, 172 (61.2%) participants had experienced various stressful life events, and 98 (34%) participants had had traumatic experiences before the onset. Furthermore, the participants who had had stressful life events showed more contamination/fear symptoms compared with those without such life events. Meanwhile, the patients who had had specific traumatic experiences showed a tendency toward hoarding obsessions. To comprehend the pathophysiology of OCD, it is important to understand the stressful life events that precede its onset.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.