ArticleMediators of inflammation2020
Investigation of Cytotoxicity, Oxidative Stress, and Inflammatory Responses of Tantalum Nanoparticles in THP-1-Derived Macrophages.
Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Role of Cellular-Ferroptosis-Mediated HMGB1 Nuclear Translocation in Indium-Tin-Oxide-Nanoparticle-Induced Inflammatory Lung Injury.Environment & health (Washington, D.C.) · 2026Article
- Progress and challenges of tantalum-containing biomaterials in regenerative medicine applications.Journal of materials science. Materials in medicine · 2026Review
- Synergistic integration of biomaterials in orthopedic implantation for infection preventing and tissue engineering.Regenerative biomaterials · 2026Review
- Research to Improve Fixed Orthodontic Treatment of Thirty Six Angle Class II Severe Malocclusions with Premolar Extractions Using a Modified Orthodontic Scientific Simulator.Bioengineering (Basel, Switzerland) · 2025Article
- Advances in Cytotoxicity Testing: From In Vitro Assays to In Silico Models.International journal of molecular sciences · 2025Review
- Review
- Cytotoxicity and Oxidative Stress Induced by Technology-Critical ElementsEnvironmental science & technology · 2025Article
- The effects of photochemical aging and interactions with secondary organic aerosols on cellular toxicity of combustion particles.Journal of aerosol science · 2025Article
- A tantalum-containing zirconium-based metallic glass with superior endosseous implant relevant properties.Bioactive materials · 2024Article
- In Vitro Biocompatibility of the Novel Ceramic Composite Baghdadite for Defect Augmentation in Revision Total Hip Arthroplasty.Journal of functional biomaterials · 2023Article
- Functional attachment of primary neurons and glia on radiopaque implantable biomaterials for nerve repair.Nanomedicine : nanotechnology, biology, and medicine · 2023Article
- Article
- Radiopaque Implantable Biomaterials for Nerve Repair.bioRxiv : the preprint server for biology · 2023Article
- Research progress and clinical translation of three-dimensional printed porous tantalum in orthopaedics.Biomaterials translational · 2023Review
- Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicityJournal of orthopaedic translation · 2023Article
- Article
- Why Is Tantalum Less Susceptible to Bacterial Infection?Journal of functional biomaterials · 2022Article
- Advances in surface modification of tantalum and porous tantalum for rapid osseointegration: A thematic review.Frontiers in bioengineering and biotechnology · 2022Review
- Fabrication of Smart Tantalum Carbide MXene Quantum Dots with Intrinsic Immunomodulatory Properties for Treatment of Allograft Vasculopathy.Advanced functional materials · 2021Article
- Frictional Properties of the TiNbTaZrO Orthodontic Wire-A Laboratory Comparison to Popular Archwires.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tantalum (Ta) is gaining attention as a biomaterial in bone tissue engineering. Although the clinical advantage of Ta-based implants for primary and revision total joint replacement (TJA) has been well documented, few studies investigated the effect of wear products of Ta implants on peri-implant cells, and their potential contribution to aseptic implant loosening. This study is aimed at examining the cytotoxicity, oxidative stress, and proinflammatory potential of Ta and TiO
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.