ArticleAfrican journal of health sciences
Childhood autism spectrum disorder: insights from a tertiary hospital cohort in Kenya.
Article in African journal of health sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Comprehensive Intervention and Effect of Martial Arts Routines on Children with Autism.Journal of environmental and public health · 2022Trial
- Pathways and delays in the diagnosis of autism spectrum disorder in Kenya: a cross-sectional study from tertiary hospitals in Nairobi.Child and adolescent psychiatry and mental health · 2025Article
- A bibliometric analysis of autism spectrum disorder signaling pathways research in the past decade.Frontiers in psychiatry · 2024Article
- The genetic landscape of autism spectrum disorder in the Middle Eastern population.Frontiers in genetics · 2024Article
- Microbes and Mental Illness: Past, Present, and Future.Healthcare (Basel, Switzerland) · 2023Review
- Early detection of neurodevelopmental disorders in African children living in informal settlements in Nairobi.BMJ paediatrics open · 2023Article
- Diagnosis and treatment challenges of autism spectrum disorder at a reference hospital in Douala, Cameroon.BMC pediatrics · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
introductionAutism spectrum disorder (ASD) is characterized by impairments in behavior, social communication, and interaction. There is little data on ASD from sub-Saharan Africa (SSA) describing clinical characteristics in large cohorts of patients. Preliminary studies report a high male sex ratio, excess of nonverbal cases, possible infectious etiologies, and comorbidities e.g. epilepsy.
objectiveTo describe the clinical characteristics of children diagnosed with ASD in an African context.
methodsA retrospective medical chart review identified 116 children diagnosed with ASD according to DSM-5 criteria at a pediatric neurology clinic in Nairobi, Kenya.
resultsThe male to female ratio was 4.3:1. The median age at presentation was 3 years with speech delay as the most common reason for presentation. Expressive language delay was observed in 90% of the population. Sixty percent who obtained imaging had normal MRI brain findings. Only 44% and 34% of children had access to speech therapy and occupational therapy respectively. Epilepsy and ADHD were the most prevalent comorbidities.
conclusionAn early median age at presentation and preponderance of male gender is observed. Access to speech therapy and other interventions was low. A prospective study would help determine outcomes for similar children following appropriate interventions.
Indexed as
Identifiers
33343175PMC7746135What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.