Evidence map›Paper›PMID 33342561›Full record

ReviewAnais brasileiros de dermatologia

Plasmacytoid dendritic cells in dermatology.

Natasha Favoretto Dias de Oliveira, Claudia Giuli Santi, Celina Wakisaka Maruta, Valeria Aoki

Open access · goldAbstract readReview
In one paragraph

Review in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Natasha Favoretto Dias de OliveiraDepartment of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: natasha.favoretto@gmail.com.
Claudia Giuli SantiDepartment of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.
Celina Wakisaka MarutaDepartment of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.
Valeria AokiDepartment of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and dendritic cells and inducing activation and migration of natural killer cells. Plasmacytoid dendritic cells also exert a role as antigen-presenting cells, promote T-lymphocyte responses, immunoregulation, plasma cells differentiation and antibody secretion. Even though plasmacytoid dendritic cells are not usually present in normal skin, their presence is detected in healing processes, viral infections, and inflammatory, autoimmune, and neoplastic diseases. In recent years, the presence of plasmacytoid dendritic cells in several dermatological diseases has been described, enhancing their potential role in the pathogenesis of such conditions. Future studies on the role of plasmacytoid dendritic cells in dermatology may lead to new therapeutic targets.

Indexed as

DermatologyInterferon Type IDendritic CellsHumansImmunity, InnateT-LymphocytesInterferon Type IAdaptive immunityDendritic cellsDermatological diseasesDermatologyInnate immunity

Identifiers

PMID33342561
PMCPMC7838105
OpenAlexW3107096966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.