Evidence map›Paper›PMID 33341876›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2021

Three-Year Reliability of MEG Visual and Somatosensory Responses.

Marie C McCusker, Brandon J Lew, Tony W Wilson

Open access · bronzeAbstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marie C McCuskerInstitute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE, 68010, USA.
Brandon J LewInstitute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE, 68010, USA.
Tony W WilsonInstitute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE, 68010, USA.
Boys Town National Research Hospital · US

Funding

DEVELOPMENTAL MULTIMODAL IMAGING OF NEUROCOGNITIVE DYNAMICS (DEV-MIND)R01MH121101 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2019 to 2023
$5.8M
MULTIMODAL IMAGING OF NEUROHIV DYNAMICS (MIND): AN OMAHA-PITTSBURGH CONSORTIUMR01MH118013 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2022
$4.9M
SIGNATURES OF CANNABIS ABUSE IN NEUROHIV (SCAN): AN INTEGRATED MOLECULAR AND IMAGING APPROACHR01DA047828 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BECKER, JAMES T., FOX, HOWARD S · 2018 to 2022
$4.5M
THE PROGRESSIVE ELEVATION OF SPONTANEOUS CORTICAL ACTIVITY IN HAND (PESCAH) PROJECTR01MH116782 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2022
$3.4M
Neurophysiological markers of HAND and the impact of aging: Evidence from MEGR01MH103220 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2014 to 2018
$2.5M
THE IMPACT OF SPONTANEOUS CORTICAL ACTIVITY ON NEURAL OSCILLATIONS AND BEHAVIORAL PERFORMANCE: EVIDENCE FROM HIGH-DEFINITION TDCS AND MEGRF1MH117032 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2018
$2.4M
The impact of chronic cannabis use on neuromagnetic activity in persons living with HIVF30DA048713 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI LEW, BRANDON J. · 2019 to 2022
$179k
NIDA NIH HHS F30 DA048713NIDA NIH HHS R01 DA047828NIMH NIH HHS R01 MH103220NIMH NIH HHS R01 MH116782NIMH NIH HHS R01 MH118013NIMH NIH HHS R01 MH121101NIMH NIH HHS RF1 MH117032
6 · The paper itself

Abstract

A major goal of many translational neuroimaging studies is the identification of biomarkers of disease. However, a prerequisite for any such biomarker is robust reliability, which for magnetoencephalography (MEG) and many other imaging modalities has not been established. In this study, we examined the reliability of visual (Experiment 1) and somatosensory gating (Experiment 2) responses in 19 healthy adults who repeated these experiments for three visits spaced 18 months apart. Visual oscillatory and somatosensory oscillatory and evoked responses were imaged, and intraclass correlation coefficients (ICC) were computed to examine the long-term reliability of these responses. In Experiment 1, ICCs showed good reliability for visual theta and alpha responses in occipital cortices, but poor reliability for gamma responses. In Experiment 2, the time series of somatosensory gamma and evoked responses in the contralateral somatosensory cortex showed good reliability. Finally, analyses of spontaneous baseline activity indicated excellent reliability for occipital alpha, moderate reliability for occipital theta, and poor reliability for visual/somatosensory gamma activity. Overall, MEG responses to visual and somatosensory stimuli show a high degree of reliability across 3 years and therefore may be stable indicators of sensory processing long term and thereby of potential interest as biomarkers of disease.

Indexed as

MagnetoencephalographyAdultAgedFemaleHumansMaleMiddle AgedPhotic StimulationPhysical StimulationReproducibility of ResultsSensory GatingSpatial ProcessingYoung AdultICCmagnetoencephalographyoscillationsstabilitytest–retest

Identifiers

PMID33341876
PMCPMC8023835
OpenAlexW3117763534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.